4 documents found, page 1 of 1
Solid and aqueous magnetoliposomes as nanocarriers for a new potential drug act...
Rodrigues, Ana Rita Oliveira; Mendes, Pedro M. F.; Silva, Pedro M. L.; Machado, Vera Alexandra Pereira; Almeida, B. G.; Araújo, João P.Iron oxide nanoparticles, with diameters around 12 nm, were synthesized by coprecipitation method. The magnetic properties indicate a superparamagnetic behavior with a coercive field of 9.7 Oe and a blocking temperature of 118 K. Both aqueous and solid magnetoliposomes containing magnetite nanoparticles have sizes below 150 nm, suitable for biomedical applications. Interaction between both types of magnetolipos...
New 1,3-diarylureas linked by C-C Suzuki coupling to the methyl 3-aminothieno[3...
Queiroz, Maria João R. P.; Peixoto, Daniela; Rodrigues, Ana Rita O.; Mendes, Pedro M. F.; Costa, Cátia N. C.; Coutinho, Paulo J. G.New six fluorescent 1,3-diarylureas linked by C-C Suzuki coupling to the 6-position of the methyl 3-aminothieno[3,2-b]pyridine-2-carboxylate moiety were prepared by reaction of the amino groups on the ortho or meta positions relative to the C-C bond of the Suzuki coupling products, with different para-substituted arylisocyanates (H, OMe, CN), in high to excellent yields. The fluorescence properties of the 1,3-d...
Magnetoliposomes based on magnetite nanoparticles
Castanheira, Elisabete M. S.; Mendes, Pedro M. F.; Coutinho, Paulo J. G.; Almeida, B. G.; Gomes, I. Tarroso; Araújo, J. P.In this work, magnetic nanoparticles of magnetite were prepared by soft chemical methods, using different surfactants as templating media. These nanoparticles were either covered with a lipid bilayer, forming dry magnetoliposomes, or entrapped in liposomes - aqueous magnetoliposomes.
Fluorescence studies on new potential antitumoral 1,3-diarylurea derivatives in...
Rodrigues, Ana Rita O.; Mendes, Pedro M. F.; Castanheira, Elisabete M. S.; Coutinho, Paulo J. G.; Peixoto, Daniela; Queiroz, Maria João R. P.Magnetic nanoparticles of magnetite and of nickel core with silica shell were prepared and either covered with a lipid bilayer or entrapped in liposomes, forming magnetoliposomes. New potential antitumoral 1,3-diarylurea derivatives of thieno[3,2-b]pyridines were then encapsulated in liposomes and magnetoliposomes and their photophysical behavior was investigated.