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Exploring in vitro efficacy of rCHAPk with antibiotic combinations, and promisi...

Tasdurmazli, Semra; Cinar, Irfan; Karamese, Murat; Aksak Karamese, Selina; Cadirci, Elif; Melo, Luís Daniel Rodrigues; Ozbek, Tulin

The increasing threat of antimicrobial-resistant bacteria, particularly Staphylococcus aureus, which rapidly develops multidrug resistance and commonly colonizes wound surfaces, demands innovative strategies. Phage-encoded endolysins offer a dual-purpose approach as topical therapies for infectious skin wounds and synergistic agents to reduce high-dose antibiotic dependence. This study explores recombinant CHAP...

Date: 2025   |   Origin: RepositóriUM - Universidade do Minho
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