3 documents found, page 1 of 1
Optimized in-solution enrichment over a million ancient human SNPs
Davidson, Roberta; Roca-Rada, Xavier; Ravinshakar, Shyamsundar; Taufik, Leonard; Haarkötter, Christian; Collen, Evelyn; Williams, Matthew P.Background In-solution hybridization enrichment of genetic markers is a method of choice in paleogenomic studies, where the DNA of interest is generally heavily fragmented and contaminated with environmental DNA, and where the retrieval of genetic data comparable between individuals is challenging. Here, we benchmark the commercial “Twist Ancient DNA” reagent from Twist Biosciences using sequencing libraries fr...
The genetic history of Portugal over the past 5.000 years
Roca-Rada, Xavier; Davidson, Roberta; Williams, Mathew P.; Villalba Mouco, Vanessa; Carvalho, António faustino; Ravinshakar, Shyamsundar; Collin, EvelynBackground Recent ancient DNA studies uncovering large-scale demographic events in Iberia have presented very limited data for Portugal, a country located at the westernmost edge of continental Eurasia. Here, we present the most comprehensive collection of Portuguese ancient genome-wide data, from 67 individuals spanning 5000 years of human history, from the Neolithic to the nineteenth century. Results We ident...
The genetic history of Portugal over the past 5,000 years.
Roca-Rada, Xavier; Davidson, Roberta; Williams, Matthew P.; Villalba-Mouco, Vanessa; Carvalho, António Manuel Faustino de; Ravishankar, ShyamsundarRecent ancient DNA studies uncovering large-scale demographic events in Iberia have presented very limited data for Portugal, a country located at the westernmost edge of continental Eurasia. Here, we present the most comprehensive collection of Portuguese ancient genome-wide data, from 67 individuals spanning 5000 years of human history, from the Neolithic to the nineteenth century. We identify early admixture...