20 documents found, page 1 of 2
An introduction to BASIC Guide
Zare Jeddi, Maryam; Jones, Kate; Leese, Elizabeth; Fustinoni, Silvia; Galea, Karen S.; Santonen, Tiina; Porras, Simo P.; Hopf, Nancy B.; Göen, ThomasHuman biomonitoring (HBM) complements air and surface measurements by integrating exposure from all routes and sources, strengthening occupational exposure assessment and control. In occupational settings, HBM can quantify exposure during routine work and nonroutine activities, evaluate controls, investigate incidents (potential overexposures), and support medical surveillance. To use HBM to its full potential,...
O ensaio do micronúcleo em células da mucosa bucal: aplicabilidade em biomonito...
Rosário, Rita Lopes; Tavares, Ana Maria; Louro, Henriqueta; Silva, Maria JoãoAs exposições ambientais e ocupacionais a alguns agentes químicos ou físicos representam sérios riscos para a saúde humana. A biomonitorização humana (BMH) permite quantificar a exposição a substâncias químicas e seus efeitos precoces através da caracterização de biomarcadores de exposição e de biomarcadores de efeito. O ensaio do micronúcleo em células bucais (MNBMCyt) é um biomarcador precoce de genotoxicidad...
An introduction to BASIC Guide: human biomonitoring and surveillance of chemica...
Zare Jeddi, Maryam; Jones, Kate; Leese, Elizabeth; Fustinoni, Silvia; Galea, Karen S.; Santonen, Tiina; Porras, Simo P.; Hopf, Nancy B.; Göen, ThomasHuman biomonitoring (HBM) complements air and surface measurements by integrating exposure from all routes and sources, strengthening occupational exposure assessment and control. In occupational settings, HBM can quantify exposure during routine work and nonroutine activities, evaluate controls, investigate incidents (potential overexposures), and support medical surveillance. To use HBM to its full potential,...
Avaliação do risco da mistura de crómio hexavalente, níquel e hidrocarbonetos a...
Tavares, Ana Maria; Viegas, Susana; Louro, Henriqueta; Goen, Thomas; Santonen, Tiina; Luijten, Mirjam; Kortenkamp, Andreas; Silva, Maria JoãoNa maioria dos contextos laborais ocorre, em geral, exposição a misturas de substâncias químicas. Este estudo, inserido na iniciativa HBM4EU, visou avaliar o risco de exposição a misturas de crómio hexavalente [Cr ( VI ) ], níquel (Ni ) e/ou hicrocarbonetos aromáticos policíclicos (HAPs ) a partir de dados de exposição reportados em estudos realizados em várias indústrias na Europa. Para a avaliação do risco de...
Occupational Exposure to Hexavalent Chromium, Nickel and PAHs: A Mixtures Risk ...
Tavares, Ana Maria; Viegas, Susana; Louro, Henriqueta; Göen, Thomas; Santonen, Tiina; Luijten, Mirjam; Kortenkamp, Andreas; Silva, Maria JoãoHexavalent chromium (Cr(VI)), nickel (Ni) and polycyclic aromatic hydrocarbons (PAHs) are genotoxic co-occurring lung carcinogens whose occupational health risk is still understudied. This study, conducted within the European Human Biomonitoring Initiative (HBM4EU), aimed at performing a mixtures risk assessment (MRA) based on published human biomonitoring (HBM) data from Cr(VI), Ni and/or PAHs occupational co-...
Occupational exposure to metals and PAHs: combining literature-based exposure a...
Tavares, Ana Maria; Alves, Inês; Moreira, Rodrigo; Louro, Henriqueta; Ladeira, Carina; Viegas, Susana; Loureiro, Susana; Santonen, Tiina; Göen, ThomasThe environment within industrial settings is commonly characterized by the existence of a complex mixture of chemicals from different raw materials and transformation processes. Occupational co-exposure to chromium (Cr), Nickel (Ni), and Polycyclic Aromatic Hydrocarbons (PAHs) may occur in diverse workplaces, such as the aeronautic and waste management, (e.g incineration) sectors. Such co-exposure rais-es conc...
HBM4EU Occupational Biomonitoring Study on e-Waste-Study Protocol
Scheepers, Paul T.J.; Duca, Radu Corneliu; Galea, Karen S.; Godderis, Lode; Hardy, Emilie; Knudsen, Lisbeth E.; Leese, Elizabeth; Louro, HenriquetaWorkers involved in the processing of electronic waste (e-waste) are potentially exposed to toxic chemicals. If exposure occurs, this may result in uptake and potential adverse health effects. Thus, exposure surveillance is an important requirement for health risk management and prevention of occupational disease. Human biomonitoring by measurement of specific biomarkers in body fluids is considered as an effec...
O projeto HBM4EU - exemplo de biomonitorização da exposição ocupacional ao crómio
Tavares, Ana Maria; Louro, Henriqueta; Silva, Maria JoãoAula 5: O projeto HBM4EU - exemplo de biomonitorização da exposição ocupacional ao crómio. Projeto HBM4EU - General objective: To understand human exposure to chemicals and resulting health impacts and communicate with policy makers to ensure that the results are exploited in the design of new chemicals policies and the evaluation of existing measures.
Combined cytotoxic and genotoxic effects of ochratoxin A and fumonisin B1 in hu...
Pinhão, Mariana; Tavares, Ana Maria; Loureiro, Susana; Louro, Henriqueta; Alvito, Paula; Silva, Maria JoãoFood products can be contaminated by several fungi species and each species may produce different mycotoxins, leading to human combined exposure. Although predictions about the joint toxic effects of mycotoxins can be made from their individual toxicities, experimental data is still limited to allow a reliable hazard assessment. Thus, this study aimed to characterize the combined cytotoxic and genotoxic effects...
Risk assessment of combined occupational exposure to hexavalent chromium, nicke...
Tavares, Ana Maria; Viegas, Susana; Louro, Henriqueta; Silva, Maria JoãoOccupational exposure is usually characterized by a complex mixture of chemicals, originating from different raw materials and transformation processes. Co-exposure to hexavalent chromium (Cr(VI)), nickel (Ni) and polycyclic aromatic hydrocarbons (PAHs) can occur in some workplaces. These substances display well-known genotoxic and carcinogenic effects, especially in the respiratory tract, sharing similar modes...