15 documents found, page 1 of 2
Detection of tick-borne pathogens in Rhipicephalus bursa ticks collected from t...
Barradas, PF; Marques, J; Tavares, C; Brito, NV; Mesquita, JRThe Garrano is a semi-feral horse breed native to several mountains in the northern Iberian Peninsula. Despite being endangered, this unique breed of pony has managed to survive in the wild and continues to be selectively bred, highlighting their remarkable resilience and adaptability to harsh environments. Wildlife plays a critical role in the survival of tick vectors in their natural habitats and the transfer...
A Single Digestion Procedure for Determination of Major, Trace, and Rare Earth ...
Carvalho, L; Reis, AT; Soares, E; Tavares, C; Monteiro, RJR; Figueira, P; Henriques, B; Vale, C; Pereira, EThe simultaneous determination of major, trace, and rare earth elements in sediments requires the development of specific procedures to prevent interferences. A single digestion method adapted from the EPA method 3051A is proposed for the quantification of 42 elements in sediments by inductively coupled plasma techniques associated with optical emission spectroscopy (ICP-OES) and mass spectrometry (ICP-MS). A c...
Association between neighbourhood green space and biological markers in school-...
Ribeiro, AI; Tavares, C; Guttentag, A; Barros, HBackground There is considerable literature on the psychological and behavioural benefits of green space. However, less is known about its health-promoting effects, as expressed on biological markers. Additionally, incorporating biomarkers into pediatric research may help elucidate the links between exposures to environmental stressors and lifelong health. Objective To measure the association between geographic...
NIS expression in thyroid tumors, relation with prognosis clinicopathological a...
Tavares, C; Coelho, MJ; Eloy, C; Melo, M; Rocha, AG; Pestana, A; Batista, R; Ferreira, LB; Rios, E; Selmi-Ruby, S; Cavadas, B; Pereira, LThyroid cancer therapy is based on surgery followed by radioiodine treatment. The incorporation of radioiodine by cancer cells is mediated by sodium iodide symporter (NIS) (codified by the SLC5A5 gene), that is functional only when targeted to the cell membrane. We aimed to evaluate if NIS expression in thyroid primary tumors would be helpful in predicting tumor behavior, response to therapy and prognosis. NIS ...
OPNa overexpression is associated with matrix calcification in thyroid cancer c...
Ferreira, LB; Lima, RT; Bastos, A; Silva, AM; Tavares, C; Pestana, A; Rios, E; Eloy, C; Sobrinho-Simões, M; Gimba, E; Soares, POsteopontin (OPN) spliced variants (OPN-SV: OPNa, OPNb, and OPNc) are aberrantly expressed in tumors and frequently associated with cancer progression. This holds true for papillary thyroid carcinoma (PTC), which is the most common type of thyroid cancer (TC). PTC often presents with desmoplasia and dystrophic calcification, including psammoma bodies (PB). This work aimed to investigate total OPN (tOPN) and OPN...
mTOR pathway in papillary thyroid carcinoma: Different contributions of mTORC1 ...
Tavares, C; Eloy, C; Melo, M; Rocha, AG; Pestana, A; Batista, R; Ferreira, LB; Rios, E; Sobrinho-Simões, M; Soares, PThe mammalian target of rapamycin (mTOR) pathway is overactivated in thyroid cancer (TC). We previously demonstrated that phospho-mTOR expression is associated with tumor aggressiveness, therapy resistance, and lower mRNA expression of SLC5A5 in papillary thyroid carcinoma (PTC), while phospho-S6 (mTORC1 effector) expression was associated with less aggressive clinicopathological features. The distinct behavior...
The Arterial Baroreflex Effectiveness Index in Risk Stratification of Chronic H...
Serôdio, JF; Oliveira, MM; Laranjo, S; Tavares, C; Cunha, PS; Abreu, A; Branco, LM; Alves, S; Rocha, I; Cruz Ferreira, RINTRODUCTION: Baroreflex function is an independent marker of prognosis in heart failure (HF). However, little is known about its relation to response to cardiac resynchronization therapy (CRT). The aim of this study is to assess arterial baroreflex function in HF patients who are candidates for CRT. METHODS: The study population consisted of 25 patients with indication for CRT, aged 65±10 years, NYHA functiona...
CYP2C19*2 and prognosis after an acute coronary syndrome: Insights from a Portu...
Teixeira, R; Monteiro, P; Marques, G; Pego, J; Lourenço, M; Tavares, C; Reboredo, A; Monteiro, S; Gonçalves, F; Ferreira, MJ; Freitas, M; Ribeiro, GBACKGROUND: Clopidogrel requires oxidation dependent on the cytochrome P450 enzyme 2C19 (CYP2C19) to form its active metabolite. The importance of loss-of-function alleles (particularly CYP2C19*2, 681G>A) in poor platelet response to clopidogrel is well recognized. OBJECTIVE: To investigate the prevalence and prognostic impact of the CYP2C19*2 allele in a local acute coronary syndrome (ACS) population. METHODS:...
O Treino de Ortostatismo (Tilt Training) Aumenta a Reserva Vasoconstritora em D...
Laranjo, S; Oliveira, MM; Tavares, C; Geraldes, V; Santos, S; Oliveira, E; Cruz Ferreira, R; Rocha, IA síncope neurocardiogénica (SNc) é uma entidade clínica comum, resultante de uma resposta autonómica reflexa excessiva durante o stress ortostático. As diferentes opções terapêuticas são controversas e de eficácia limitada. O treino de ortostatismo (TTr) tem-se mostrado uma alternativa prometedora no tratamento destes doentes (D). No entanto, permanece por esclarecer o seu mecanismo de acção e o impacto clínic...
Tilt Training Increases Vasoconstrictor Reserve in Patients with Neurocardiogen...
Laranjo, S; Oliveira, MM; Tavares, C; Geraldes, V; Santos, S; Oliveira, E; Cruz Ferreira, R; Rocha, INeurocardiogenic syncope (NCS) is a common clinical entity resulting from an excessive reflex autonomic response, particularly during orthostatism. Treatment options are controversial and of limited effectiveness. Tilt training (TT) is a promising option to treat these patients. However, its mechanism of action and clinical impact remain unclear. OBJECTIVE: To characterize hemodynamic and autonomic responses du...