24 documents found, page 1 of 3
Protocolo de intervenção à Pessoa com Asma/ DPOC na Unidade de Cuidados na Comu...
Bernardino, Dina; Tavares, Catarina; Galache, Luís; Costa, Sara; Canhão, Sónia; Vieira, Manuela; Rosa, MartaEm Portugal as Doenças Respiratórias Cronicas são uma das principais causas de morbilidade e mortalidade, com tendência para aumento da sua prevalência. O Protocolo de Reabilitação Respiratória na Unidade de Cuidados na Comunidade de Santarém perspetiva efeitos benéficos na qualidade de vida das pessoas com esta patologia e na utilização dos serviços de saúde. Projetado segundo a Metodologia do Planeamento em S...
The impact of the coronavirus disease 2019 pandemic on the utilisation of emerg...
Madanelo, Mariana; Ferreira, Carlos; Nunes-Carneiro, Diogo; Pinto, André; Rocha, Maria Alexandra; Correia, Jorge; Teixeira, Bernardo; Mendes, GonçaloObjectives: To compare the number of patients attending the Urology Emergency Department (ED) of the Centro Hospitalar Universitário do Porto (CHUP), as well as their demographic characteristics, the reasons for admission, the clinical severity under the Manchester triage system (MTS), and the need for emergency surgery or hospitalisation, during the coronavirus disease 2019 (COVID-19) pandemic and the equivale...
Methodological approach to assess biodiversity in agro ecosystems – A case study
Tavares, Catarina; Gouveia, Ana F.; Crespo, Luís; Mateus, Célia; Rebelo, M. TeresaIn agroecosystems, the evaluation of biodiversity is extremely important given its relation with their sustainability, however it is a difficult and expensive task. The use of the higher taxa surrogacy has been proposed as an effective and less expensive way to assess biodiversity, but is still being used mainly in natural, more stable, ecosystems. In this study, we tested the use of the higher taxa surrogacy a...
NIS expression in thyroid tumors, relation with prognosis clinicopathological a...
Tavares, Catarina; Coelho, Maria João; Eloy, Catarina; Melo, Miguel; da Rocha, Adriana Gaspar; Pestana, Ana; Batista, Rui; Ferreira, Luciana BuenoThyroid cancer therapy is based on surgery followed by radioiodine treatment. The incorporation of radioiodine by cancer cells is mediated by sodium iodide symporter (NIS) (codified by the SLC5A5 gene), that is functional only when targeted to the cell membrane. We aimed to evaluate if NIS expression in thyroid primary tumors would be helpful in predicting tumor behavior, response to therapy and prognosis. NIS ...
mTOR Pathway in Papillary Thyroid Carcinoma: Different Contributions of mTORC1 ...
Tavares, Catarina; Eloy, Catarina; Melo, Miguel; Gaspar da Rocha, Adriana; Pestana, Ana; Batista, Rui; Bueno Ferreira, Luciana; Rios, ElisabeteThe mammalian target of rapamycin (mTOR) pathway is overactivated in thyroid cancer (TC). We previously demonstrated that phospho-mTOR expression is associated with tumor aggressiveness, therapy resistance, and lower mRNA expression of SLC5A5 in papillary thyroid carcinoma (PTC), while phospho-S6 (mTORC1 effector) expression was associated with less aggressive clinicopathological features. The distinct behavior...
TERT promoter mutations are a major indicator of poor outcome in differentiated...
Melo, Miguel; Gaspar Da Rocha, Adriana; Vinagre, João; Batista, Rui; Peixoto, Joana; Tavares, Catarina; Celestino, Ricardo; Almeida, AnaContext: Telomerase promoter mutations (TERT) were recently described in follicular cell-derived thyroid carcinomas (FCDTC) and seem to be more prevalent in aggressive cancers. Objectives: We aimed to evaluate the frequency of TERT promoter mutations in thyroid lesions and to investigate the prognostic significance of such mutations in a large cohort of patients with differentiated thyroid carcinomas (DTCs). De...
A methanolic extract of Ganoderma lucidum fruiting body inhibits the growth of ...
Oliveira, Beatriz; Reis, Filipa S.; Sousa, Diana; Tavares, Catarina; Lima, Raquel T.; Ferreira, Isabel C.F.R.; Santos, Tiago; Vasconcelos, M. HelenaGanoderma lucidum is one of the most extensively studied mushrooms as a functional food and as a chemopreventive agent due to its recognized medicinal properties. Some G. lucidum extracts have shown promising antitumor potential. In this study, the bioactive properties of various extracts of G. lucidum, from both the fruiting body and the spores, were investigated. The most potent extract identified was the met...
Suillus luteus methanolic extract inhibits cell growth and proliferation of a c...
Santos, Tiago; Tavares, Catarina; Sousa, Diana; Vaz, Josiana A.; Calhelha, Ricardo C.; Martins, Anabela; Almeida, Gabriela M.; Ferreira, Isabel C.F.R.Several edible mushrooms extracts are known to have tumour cell growth inhibitory potential. The objective of this work was to study this potential in extracts of Suillus luteus collected from the Northeast of Portugal. Various extracts were prepared and their effect on tumour cell growth was studied with the SRB assay in four human tumour cell lines: MCF-7 (breast), NCI-H460 (non-small cell lung cancer), AGS (...
Suillus luteus methanolic extract inhibits cell growth and proliferation of a c...
Santos, Tiago dos; Tavares, Catarina; Sousa, Diana; Vaz, Josiana A.; Calhelha, Ricardo C.; Martins, Anabela; Almeida, Gabriela M.Several edible mushrooms extracts are known to have tumor cell growth inhibitory potential. The objective of this work was to study this potential in extracts of Suillus luteus collected from the Northeast of Portugal. Various extracts were prepared and their effect on tumor cell growth was studied with the SRB assay in four human tumor cell lines: MCF-7 (breast), NCI-H460 (non-small cell lung cancer), AGS (gas...
Gonoderma luicidium methanolic extract: chemical characterization in phenolic c...
Heleno, Sandrina A.; Tavares, Catarina; Vaz, Josiana A.; Almeida, Gabriela M.; Martins, Anabela; Queiroz, Maria João R. P.; Vasconcelos, M. HelenaFundação para a Ciência e a Tecnologia (FCT, Portugal) and COMPETE/QREN/UE (research project PTDC/AGR-ALI/110062/2009 and research unities PEst-C/QUI/UI0686/2011 and PEst-OE/AGR/UI290/2011) and S.A. Heleno PhD grant (BD/70304/2010) also financed by POPH and FSE