16 documents found, page 1 of 2
Polymicrobial interactions influence the agr copy number in Staphylococcus aure...
Matias, C; Serrano, I; Van-Harten, S; Mottola, C; Mendes, J; Tavares, L; Oliveira, MDiabetic foot ulcers are a major complication of diabetes and are often colonised by complex bacterial communities, where Staphylococcus aureus is frequently co-present with Pseudomonas aeruginosa. These bacteria interact through quorum sensing, encoded in S. aureus by the accessory gene regulator (agr). Typing and copy number of S. aureus agr were assessed here to give insights on strain variability and possib...
The who-when-why triangle of CAM use among Portuguese IBD patients
Portela, F; Dias, C; Caldeira, P; Cravo, M; Deus, JR; Gonçalves, R; Lago, P; Morna, H; Peixe, P; Ramos, J; Sousa, H; Tavares, L; Vasconcelos, HThe use of complementary and alternative medicines is increasing among chronic patients, particularly those afflicted with inflammatory bowel diseases. AIM: This study aimed to address the prevalence of complementary and alternative medicines use among Portuguese inflammatory bowel diseases' patients. METHODS: Patients were invited to fill an anonymous questionnaire concerning the use of complementary and alter...
The Who-When-Why Triangle of CAM Use Among Portuguese IBD Patients
Portela, F; Dias, C; Caldeira, P; Cravo, M; Deus, J; Gonçalves, R; Lago, P; Morna, H; Peixe, P; Ramos, J; Sousa, H; Tavares, L; Vasconcelos, H; Magro, FBACKGROUND: The use of complementary and alternative medicines is increasing among chronic patients, particularly those afflicted with inflammatory bowel diseases. AIM: This study aimed to address the prevalence of complementary and alternative medicines use among Portuguese inflammatory bowel diseases' patients. METHODS: Patients were invited to fill an anonymous questionnaire concerning the use of complementa...
Mês da prevenção dos maus tratos na infância
Escobar, C; Fonseca, F; Almeida, H; Romeiro, J; Tavares, L; Torre, ML; Ezequiel, M; Santos, P; Vidal, T; Silva, T
Molecular Typing, Virulence Traits and Antimicrobial Resistance of Diabetic Foo...
Mottola, C; Semedo-Lemsaddek, T; Mendes, JJ; Melo-Cristino, J; Tavares, L; Cavaco-Silva, P; Oliveira, MDiabetes mellitus is a major chronic disease that continues to increase significantly. One of the most important and costly complications of diabetes are foot infections that may be colonized by pathogenic and antimicrobial resistant bacteria, harboring several virulence factors, that could impair its successful treatment. Staphylococcus aureus is one of the most prevalent isolate in diabetic foot infections, t...
Susceptibility Patterns of Staphylococcus Aureus Biofilms in Diabetic Foot Infe...
Mottola, C; Matias, C; Mendes, JJ; Melo-Cristino, J; Tavares, L; Cavaco-Silva, P; Oliveira, MBACKGROUND: Foot infections are a major cause of morbidity in people with diabetes and the most common cause of diabetes-related hospitalization and lower extremity amputation. Staphylococcus aureus is by far the most frequent species isolated from these infections. In particular, methicillin-resistant S. aureus (MRSA) has emerged as a major clinical and epidemiological problem in hospitals. MRSA strains have t...
IL23R polymorphisms influence phenotype and response to therapy in patients wit...
Cravo, M; Ferreira, P; Sousa, P; Moura-Santos, P; Velho, S; Tavares, L; Deus, JR; Ministro, P; Peixe, P; Correia, L; Velosa, J; Maio, R; Brito, MOBJECTIVE: We aimed to identify the clinical and genetic [IL23 receptor (IL23R) single nucleotide polymorphisms (SNPs)] predictors of response to therapy in patients with ulcerative colitis. PATIENTS AND METHODS: A total of 174 patients with ulcerative colitis, 99 women and 75 men, were included. The mean age of the patients was 47±15 years and the mean disease duration was 11±9 years. The number of patients cl...
Clinical and genetic factors predicting response to therapy in patients with Cr...
Cravo, M; Ferreira, P; Sousa, P; Moura-Santos, P; Velho, S; Tavares, L; Deus, JR; Ministro, P; Silva, J; Correia, L; Velosa, J; Maio, R; Brito, MAIM:To identify clinical and/or genetic predictors of response to several therapies in Crohn's disease (CD) patients. METHODS:We included 242 patients with CD (133 females) aged (mean ± standard deviation) 39 ± 12 years and a disease duration of 12 ± 8 years. The single-nucleotide polymorphisms (SNPs) studied were ABCB1 C3435T and G2677T/A, IL23R G1142A, C2370A, and G9T, CASP9 C93T, Fas G670A and LgC844T, and A...
Phenotype-genotype profiles in Crohn's disease predicted by genetic markers in ...
Durães, C; Machado, J; Portela, F; Rodrigues, S; Lago, P; Cravo, M; Ministro, P; Marques, M; Cremers, I; Freitas, J; Cotter, J; Tavares, L; Matos, LBACKGROUND: About 70 loci are associated with susceptibility to Crohn's disease (CD), particularly in pathways of innate immunity, autophagy, and pathogen recognition. Phenotype-genotype associations are inconsistent. METHODS: CD susceptibility polymorphisms ATG16L1 rs2241880, ICAM1 rs5498, IL4 rs2070874, IL17F rs763780, IRGM rs13361189, ITLN1 rs2274910, LRRK2 rs11175593, and TLR4 rs4986790 were genotyped in a ...
Formação em Gestão de Risco e Segurança do Doente
Marinho, A; Barata, F; Bordalo, I; Tavares, L; Trindade, L; Lage, MJ; Ramos, SA Gestão do Risco define-se como a cultura, processos e estruturas que sustentam a gestão efetiva de potenciais oportunidades e efeitos adversos, implicando a definição e a utilização de vários instrumentos que permitem a identificação e a avaliação dos riscos (gestão de risco proactiva) e a deteção e análise de incidentes (gestão de risco reativa). A premência de disponibilizar formação sobre Gestão do Risco e...