Endometrial adenocarcinoma is one of the most frequent malignant neoplasms of the female genital tract in Western Europe and North America. More than 90% of cases occur in women over 50 years-old, however, 4% of cases occur before 40 years-old. The present clinical case concerns a 74 years-old woman with blood loss, a vaginal ulcerated lesion, and an enlarged uterus. She consequently underwent a colpocytology, ...
Adenoid cystic carcinoma in Bartholin’s gland is a rare malignant gynecologic tumor that appears as a solid lesion, movable and painful, with slow growth. It is a tumor associated with frequent local recurrence and metastasis, which can occur several years after the primary lesion. The clinical diagnosis includes cystic lesion or abscess. However, it has a very particular morphologic presentation, which allows ...
The Waste Framework Directive (WFD) proposes a Waste Hierarchy (WH), a list of waste management strategies ordered from the most to the least preferable and often illustrated as an inverted pyramid. Waste prevention is at the top of this pyramid, followed by preparing for reuse, recycling, and then other recovery activities such as waste to energy. At the bottom of this hierarchy, the waste management strategy ...
Background: Axial spondyloarthritis (axSpA), particularly ankylosing spondylitis was historically considered a male’s disease and has been under-recognized in women. Emerging evidence reveals sex differences in pathophysiology, disease presentation and therapeutic efficacy. Objective: To identify differences between sexes in a Portuguese cohort of patients with axSpA regarding clinical manifestations, disease a...
OBJECTIVE: To establish Portuguese recommendations regarding the indication to perform DXA and to initiate medication aimed at the prevention of fragility fractures. METHODS: A multidisciplinary panel, representing the full spectrum of medical specialties and patient associations devoted to osteoporosis, as well as national experts in this field and in health economics, was gathered to developed recommendations...
Rheumatic and musculoskeletal diseases (RMD) are prevalent and leading causes of disability and consumption of healthcare and social resources. EpiReumaPt is a national population-based survey developed by the Portuguese Society of Rheumatology that aimed to estimate the prevalence of RMDs and determine their impact on function, quality of life, mental health and use of healthcare resources. This article descri...
Biotechnological drugs have become a fundamental resource for the treatment of rheumatic patients. Patent expiry of some of these drugs created the opportunity for biopharmaceutical manufacturers to develop biosimilar drugs intended to be as efficacious as the originator product but with a lower cost to healthcare systems. Due to the complex manufacturing process and highly intricate structure of biologicals, a...
Fibromyalgia (FM) is a very frequent syndrome of unknown cause, characterized by generalized pain, fatigue and a number of tender points to palpation. Among the several etiopathogenic hypotheses discussed, the association of FM with some viral infections has been the object of multiple studies due to its relation and similarity with the chronic fatigue syndrome, acknowledges as being related, although not exclu...