Generalized pustular psoriasis (GPP) is a rare but severe inflammatory skin disease characterized by the eruption of widespread sterile pustules, often accompanied by systemic inflammation. Although GPP can coexist with plaque psoriasis, it is increasingly recognized as a distinct entity with unique clinicopathological, immunologic, and genetic features. The dysregulated IL-36 pathway, including mutations in th...
Introduction: Psoriasis is a common, chronic, and inflammatory skin disorder with a high personal, social and economic burden and important implications for healthcare systems. The aim of this study was to provide an epidemiological characterization of individuals with psoriasis in Portugal.Material and Methods: A large observational, cross-sectional, nationwide, population-based survey study developed by the P...
Introduction: Psoriasis is a common, chronic, and inflammatory skin disorder with a high personal, social and economic burden and important implications for healthcare systems. The aim of this study was to provide an epidemiological characterization of individuals with psoriasis in Portugal. Methods: A large observational, cross-sectional, nationwide, population-based survey study developed by the Portuguese Ps...
Introduction: Psoriasis is a common, chronic, and inflammatory skin disorder with a high personal, social and economic burden and important implications for healthcare systems. The aim of this study was to provide an epidemiological characterization of individuals with psoriasis in Portugal. Material and methods: A large observational, cross-sectional, nationwide, population-based survey study developed by the ...
Psoriasis is a highly prevalent chronic, inflammatory multisystem disease with a considerable impact on patients' quality of life and the healthcare system. This report presents the recommendations developed by the Portuguese Psoriasis Group of the Portuguese Society of Dermatology and Venereology that address several clinical questions arising during the management and care of psoriasis with biologic therapy, ...
A spectrum of skin conditions – inflammatory, preneoplastic and neoplastic in nature – have been reported to occur as late side effects of radiation therapy. Postiradiation multiple minute digitate porokeratosis (PIMMDP), although seldom reported, has emerged as a distinctively unique variant among porokeratoses. The case of a 47-year-old Caucasianwoman who developed multiple filiform spiny papules mainly over ...
Vitiligo is an acquired prevalent pigmentary disorder characterized by its chronicity, refractoriness and significant psychosocial burden. Concerning its pathogenesis, several genetic, environmental, oxidative stress mechanisms and immune disturbances combine in an intricate, complex way. Diverse immunemediated comorbidities do occur in a variable yet significant manner, so as to fully justify the careful appro...
Presently, medical practice - increasingly scrutinized by society - is marked by several constraints and limitations of financial, regulatory, bureaucratic and administrative nature. This restrictive, highly regulated environment, that does subvert classical medical practice, vividly contrasts with the laxity by which diverse nonqualified paramedic professionals of the aesthetic area and of the so called comple...
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