2 documents found, page 1 of 1
Transmural remission improves clinical outcomes up to 5 years in Crohn's disease
Fernandes, Samuel; Serrazina, Juliana; Botto, Inês Ayala; Leal, Tiago; Guimarães, Andreia; Garcia, Joana Lemos; Rosa, Isadora; Prata, RitaIntroduction: Evidence supporting transmural remission (TR) as a long-term treatment target in Crohn's disease (CD) is still unavailable. Less stringent but more reachable targets such as isolated endoscopic (IER) or radiologic remission (IRR) may also be acceptable options in the long-term. Methods: Multicenter retrospective study including 404 CD patients evaluated by magnetic resonance enterography and colon...
Serum dipeptidyl peptidase 4 : a predictor of disease activity and prognosis in...
Pinto Lopes, Pedro; Afonso, Joana; Pinto Lopes, Rui; Rocha, Cátia; Lago, Paula; Gonçalves, Raquel; Tavares de Sousa, Helena; Macedo, GuilhermeBackground: Serum dipeptidyl peptidase 4 (DPP-4) has drawn particular interest as a biomarker in inflammatory bowel disease (IBD), as this protease inactivates several peptides that participate in the inflammatory cascade. Methods: Two prospectively recruited cohorts consisting of 195 patients (101 had Crohn’s disease [CD] and 94 had ulcerative colitis [UC]) were evaluated using clinical indexes and followed up...