2 documents found, page 1 of 1
N-Glycans as fundamental immune-checkpoints at the frontiers of inflammation, a...
Azevedo, CM; Santos-Pereira, B; Leite-Gomes, E; Rodrigues, CS; Dantas, CS; Faria, G; Nogueira, R; Almeida, P; Tavares-Gomes, L; Gaifem, J; Alves, IOs glicanos revestem a superfície de praticamente todas as células, dando origem ao chamado glicocálice. Os glicanos, e particularmente os N- glicanos, são peças-chave na definição do destino e da natureza da resposta imune, participando tanto de vias pró-inflamatórias quanto anti-inflamatórias presentes em processos inflamatórios, autoimunes e no câncer. Os glicanos e as proteínas de ligação a glicanos (GBPs) ...
The role of glycans in health and disease: Regulators of the interaction betwee...
Crouch, LI; Rodrigues, CS; Bakshani, CR; Tavares-Gomes, L; Gaifem, J; Pinho, SSThe human gut microbiota is home to a diverse collection of microorganisms that has co-evolved with the host immune system in which host-microbiota interactions are essential to preserve health and homeostasis. Evidence suggests that the perturbation of this symbiotic host-microbiome relationship contributes to the onset of major diseases such as chronic inflammatory diseases including Inflammatory Bowel Diseas...