4 documents found, page 1 of 1
Anti-algics in the therapeutic response of breast and urological cancers
Matos, Ana Catarina; Lorigo, João; Marques, Inês Alexandra; Abrantes, Ana Margarida; Jóia-Gomes, Matilde; Sá-Couto, Pedro; Gonçalves, Ana CristinaThe effect of anti-algics on tumor progression and the overall survival of patients is controversial and remains unclear. Herein, we disclose the in vitro effects of the local anesthetics lidocaine, ropivacaine, and levobupivacaine on breast (MCF7), prostate (PC3, LNCaP), and bladder (TCCSUP, HT1376) cancer cell lines, both as monotherapy and in combination with standard-of-care therapeutics. Assays for cell pr...
The Effect of Circumcision on Male Sexual Function
Lourenço, Mário; Carvalho, João; Tavares-Silva, Edgar; Parada, Belmiro; Figueiredo, ArnaldoIntroduction: The effect of circumcision on male sexual function is controversial and may have positive or negative effects on various domains of sexuality (erectile function, ejaculation, orgasm, desire). We aimed to assess the sexual function before circumcision and after circumcision. Methods: The sample was composed for all patients circumcised by the same surgeon (principal investigator) in the last 26 mon...
Probiotic supplementation in marathonists and its impact on lymphocyte populati...
Batatinha, Helena; Tavares-Silva, Edgar; Leite, Geovana S. F.; Resende, Ayane S.; Albuquerque, José A. T.; Arslanian, Christina; Fock, Ricardo A.Made available in DSpace on 2021-06-25T11:02:44Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-12-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Probiotic supplementation arises as playing an immune-stimulatory role. High-intensity and -volume exercise can inhibit immune cell function, which threatens athletic performance and recovery. We hypothesized that 30 days of probiotic supple...
A Possible New Molecule For Diagnosis and Follow Uo of Bladder Cancer: The Radi...
Tavares-Silva, Edgar; Ferreira, Sara; Abrantes, Ana Margarida; Brito, Ana; Laranjo, Mafalda; Metello, Luís F.; Zeevart, Jan; Louw, WernerIntroduction: The polymer PEI-MP (polyethyleneimine, functionalised with methylphosphonate groups) was initially synthesized for palliative therapy of bone metastases after convenient radiolabelling. However, in biodistribution studies performed with this polymer radiolabelled with different radionuclides, was obvious a higher uptake by the bladder wall, that might demonstrate a certain selectivity to bladder c...