2 documents found, page 1 of 1
Exploring Cannabidiol (CBD) and Cannabigerol (CBG) Safety Profile and Skincare ...
Luz-Veiga, M; Mendes, A; Tavares-Valente, D; Amorim, M; Conde, A; Pintado, ME; Moreira, HR; Azevedo-Silva, J; Fernandes, JCannabinoids have long been known for their bioactive properties, with their topical application as anti-inflammatory compounds being at the forefront of research for the past decade. Concurrently, the cosmetic market is a fast-growing industry in constant need of new biomolecules. In this work, we studied the safety profile for topical applications of two cannabinoids: cannabidiol (CBD) and cannabigerol (CBG) ...
Disruption of ph dynamics suppresses proliferation and potentiates doxorubicin ...
Tavares-Valente, D; Sousa, B; Schmitt, F; Baltazar, F; Queirós, OThe reverse pH gradient is a major feature associated with cancer cell reprogrammed metabolism. This phenotype is supported by increased activity of pH regulators like ATPases, carbonic anhydrases (CAs), monocarboxylate transporters (MCTs) and sodium–proton exchangers (NHEs) that induce an acidic tumor microenvironment, responsible for the cancer acid-resistant phenotype. In this work, we analyzed the expressio...