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Hydrogel-Assisted Antisense LNA Gapmer Delivery for In Situ Gene Silencing in S...
Moreno, PM; Ferreira, AR; Salvador, D; Rodrigues, MT; Torrado, M; Carvalho, ED; Tedebark, U; Sousa, MM; Amaral, IF; Wengel, J; Pêgo, APAfter spinal cord injury (SCI), nerve regeneration is severely hampered due to the establishment of a highly inhibitory microenvironment at the injury site, through the contribution of multiple factors. The potential of antisense oligonucleotides (AONs) to modify gene expression at different levels, allowing the regulation of cell survival and cell function, together with the availability of chemically modified...
Data: 2018
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Origem: Repositório Aberto da Universidade do Porto