6 documents found, page 1 of 1
The GO-DACT protocol
Vieira de-Sousa, Elsa; Canhão, Helena; Alves, P.; Maria Rodrigues, Ana; Teixeira, F.; Tavares-Costa, J.; Bernardo, A.; Pimenta, S.The GO-DACT is an investigator-initiated, multicentric randomized placebo-controlled double-blinded trial, that assesses dactylitis as primary endpoint. Psoriatic arthritis patients naïve to methotrexate and biologic disease modifying anti-rheumatic drugs, with at least one active dactylitis, were assigned to golimumab in combination with methotrexate or placebo in combination with methotrexate, for 24 weeks. B...
The Portuguese Society of Rheumatology position paper on the use of biosimilars...
Araújo, Filipe C.; Sepriano, Alexandre; Teixeira, F.; Jesus, D.; Rocha, T. M.; Martins, Paula Andreia; Tenazinha, C.; Cordeiro, A.; Mourão, A. F.Biosimilars are new and more affordable similar versions of previously approved reference biological drugs. Following the approval of the first monoclonal antibody biosimilar in 2013, the Portuguese Society of Rheumatology issued a position paper on the use of biosimilars in rheumatic conditions covering efficacy, safety, extrapolation, interchangeability, substitution and pharmacovigilance. However, as this is...
Portuguese recommendations for the use of biological therapies in patients with...
Duarte, Cátia; Sousa-Neves, J.; Águeda, A.; Ribeiro, P.; Daniel, A.; Eugénio, G.; Silvério Serra, Sofia; Araújo, F.; Barcelos, A.; Filipe, B.Objective: To update the recommendations for the treatment of rheumatoid arthritis (RA) with biological therapies, endorsed by the Portuguese Society of Rheu -matology (SPR). Methods: These treatment recommendations were formulated by Portuguese rheumatologists based on litera -ture evidence and consensus opinion. At a national meeting the 11 recommendations were discussed and updated. The document resulting fr...
Portuguese recommendations for the use of methotrexate in rheumatic diseases - ...
Duarte, Ana Catarina; Santos-Faria, D.; Gonçalves, M. J.; Sepriano, Alexandre; Mourão, A. F.; Duarte, C.; Neves, J. S.; Águeda, A. F.; Ribeiro, P. A.Background: Methotrexate (MTX) is the first-line drug in the treatment of rheumatoid arthritis (RA) and the most commonly prescribed disease modifying antirheumatic drug. Moreover, it is also used as an adjuvant drug in patients under biologic therapies, enhancing the efficacy of biologic agents. Objectives: To review the literature and update the Portuguese recommendations for the use of MTX in rheumatic disea...
The Portuguese Society of Rheumatology position paper on the use of biosimilars...
Araújo, F.C.; Sepriano, Alexandre; Teixeira, F.; Jesus, D.; Rocha, T.M.; Martins, P.; Tenazinha, C.; Cordeiro, A.; Mourão, A.F.; Silva, C.; Vaz, C.Biosimilars are new and more affordable similar versions of previously approved reference biological drugs. Following the approval of the first monoclonal antibody biosimilar in 2013, the Portuguese Society of Rheumatology issued a position paper on the use of biosimilars in rheumatic conditions covering efficacy, safety, extrapolation, interchangeability, substitution and pharmacovigilance. However, as this is...
Portuguese recommendations for the diagnosis and management of gout
Araujo, F.; Cordeiro, I; Teixeira, F.; Rovisco, João; Ramiro, Sofia; Mourão, AF; Costa, J. A.; Pimentão, J. B.; Malcata, Armando; Santos, M. J.Objective: To develop Portuguese evidence-based recommendations for the Diagnosis and Management of Gout. Methods: As part of the 3e Initiative (Evidence, Expertise and Exchange), a panel of 78 international rheumatologists developed 10 relevant clinical questions which were investigated with systematic literature reviews. MEDLINE, EMBASE, Cochrane CENTRAL and abstracts from 2010-2011 EULAR and ACR meetings wer...