The diagnosis of antibody-mediated rejection (AMR) in kidney allograft biopsies still represents a challenge for clinicians and pathologists. There are scarce reports evaluating endothelial-associated transcripts in kidney allograft biopsies by immunohistochemistry (IHC). This study aimed to evaluate the IHC expression Caveolin-1 (Cav), Von Willebrand Factor (Vwf) and T-Cadherin (Cad) in biopsies with antibody-...
Visceral leishmaniasis (VL) is an endemic parasitic disease frequently found in Northeast Brazil and may cause acute kidney injury (AKI) and glomerulonephritis. After appropriate treatment, renal function recovery may occur. We describe the rare case of a patient with VL, who developed severe AKI requiring dialysis and was subsequently diagnosed with Chagas disease coinfection. After specific treatment for VL, ...
Hepatocellular carcinoma (HCC) is a global health problem and is associated with chronic liver disease, especially in the cirrhotic phase. This tumor can be preceded by precursor lesions, namely low and high grade dysplastic nodules, and regenerative nodules, typical of cirrhosis. The current study evaluated the immunohistochemical expression of VEGF and angiopoietin-2 in HCC and precursor lesions is a single i...