13 documents found, page 1 of 2

Factors associated with short and long term cognitive changes in patients with ...

This study aimed to assess cognition in patients with severe sepsis or septic shock and whether cognitive impairment was associated with clinical and laboratory parameters. We conducted a cohort study of patients with severe sepsis and septic shock evaluated within 24 h and one year after ICU discharge. Demographic, clinical and laboratory data were analyzed, and the following neuropsychological tests were appl...

Toxoplasma gondii infection and chronic schizophrenia: is there any association?

Background: Toxoplasma gondii (T. gondii) infection has been identified as a risk factor for schizophrenia. Objectives: Herein, we sought to evaluate the association between T. gondii infection and clinical symptoms and quality of life in patients with schizophrenia. Methods: We conducted a cross-sectional study with 48 patients with chronic schizophrenia and 40 controls. Peripheral blood was drawn, and IgM and...

Post-sepsis cognitive impairment and associated risk factors : a systematic rev...

Introduction: Post-sepsis cognitive impairment is one of the major sequelae observed in survivors ofsepsis. This cognitive impairment can be global or may affect specific domains. A better understandingof these deficits and associated risk factors could influence the care of patients with sepsis.Objective: To perform a systematic review to investigate the presence of cognitive impairment and itsassociated risk ...

Parkinsonian signs and symptoms in adults with a history of Sydenham’s chorea.

Background: Sydenham’s chorea is associated with dysfunction of fronto-striatal circuits induced by crossreactive antibodies to group A b-hemolytic streptococcus. High susceptibility of extrapyramidal effects of neuroleptics in patients with Sydenham’s chorea suggests underlying nigro-striatal dysfunction. Objective: To study the presence of parkinsonism in patients with a history of Sydenham’s Chorea. Methods:...

Lithium Decreases Plasma Adiponectin Levels in Bipolar Depression

Paracoccidioidomycosis case series with and without central nervous system invo...

Introduction: Paracoccidioidomycosis (PCM) is the most important systemic mycosis in South America. Central nervous system involvement is potentially fatal and can occur in 12.5% of cases. This paper aims to contribute to the literature describing eight cases of neuroparacoccidioidomycosis (NPMC) and compare their characteristics with patients without neurological involvement, to identify unique characteristics...

Borderline personality features possibly related to cingulate and orbitofrontal...

Prefrontal cortex dysfunction has been associated with a series of behavioral symptoms, such as impulsivity and affective instability, which are the defining features of several personality disorders, notably, borderline personality disorder. We report on a 27-year-old patient with schizencephaly in the right frontal lobe (cingulate cortex lesion and secondary orbitofrontal cortex dysfunction) presenting with p...

Um jogador patológico por Dostoiévski.

O livro “O jogador” de Fiódor Dostoiévski narra um caso de jogo patológico bastante representativo. O percurso do personagem principal, Aleksei Ivanovitch, evidencia a dramática evolução do transtorno com três fases bem definidas: ganho, perdas e desespero. Partindo do conceito freudiano de narcisismo articulado aos conceitos da psicologia do self de Heinz Kohut, das teorias de Donald Winnicott e Wilfred Bion, ...

Serum hyaluronan and collagen IV as non-invasive markers of liver fibrosis in p...

Non-invasive markers of fibrosis have been used to diagnose liver fibrosis in a variety of diseases. Hyaluronic acid (HA) and collagen IV (C-IV) levels were measured in the sera of patients from an endemic area for schistoso¬miasis in Brazil to diagnose and to rank the intensity of liver fibrosis. Seventy-nine adult patients with schistoso¬miasis, in the age range of 21-82 years (49 ± 13.4) were submitted to cl...

Plasmodium berghei NK65 induces cerebral leukocyte recruitment in vivo : an int...

Malaria is second only to tuberculosis as the leading cause of morbidity and mortality as a consequence of a single infectious agent. Much of the pathology of malaria arises from the inappropriate or excessive immune response mounted by the host in an attempt to eliminate the parasite. We here report the inflammatory changes observed in the cerebral microvasculature of C57BL/6 and BALB/c mice that had been inoc...