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Vaccination with a CD4+ and CD8+ T-cell epitopes-based recombinant chimeric pro...

Mendes, Tiago A. O.; Dias, Daniel S.; Ribeiro, Patrícia A. F.; Martins, Vívian T.; Lage, Daniela P.; Costa, Lourena E.; Chávez-Fumagalli, Miguel A.

Vaccination seems to be the best approach to control visceral leishmaniasis (VL). Resistance against infection is based on the development of a Th1 immune response characterized by the production of interferons-γ (IFN-γ), interleukin-12 (IL-12), granulocyte-macrophage-colony-stimulating factor (GM-CSF), and tumor necrosis factor-α (TNF-α), among others. A number of antigens have been tested as potential targets...

Date: 2018   |   Origin: Oasisbr

Early psychiatric morbidity in a Brazilian sample of acute ischemic stroke pati...

Pedroso, Vinicius S.P.; Brunoni, Andre R.; Vieira, Érica L.M.; Jorge, Ricardo E.; Lauterbach, Edward C.; Teixeira, Antonio L.

OBJECTIVE: Stroke is a major public health problem worldwide, and its neuropsychiatric sequelae are frequent and disabling. Furthermore, there is evidence that these sequelae impair recovery. Brazil has the highest stroke rates in Latin America, but data on the frequency of neuropsychiatric disorders in these patients are scarce. This study aimed to identify mental disorders among in-hospital patients with acut...

Date: 2018   |   Origin: Oasisbr

Environmental enrichment restores cognitive deficits induced by experimental ch...

Barichello, Tatiana; Fagundes, Glauco D.; Generoso, Jaqueline S.; Dagostin, Caroline S.; Simões, Lutiana R.; Vilela, Márcia C.; Comim, Clarissa M.

To evaluate the influence of environmental enrichment (EE) on memory, cytokines, and brain-derived neurotrophic factor (BDNF) in the brain of adult rats subjected to experimental pneumococcal meningitis during infancy. On postnatal day 11, the animals received either artificial cerebrospinal fluid (CSF) or Streptococcus pneumoniae suspension intracisternally at 1 × 106 CFU/mL and remained with their mothers unt...

Date: 2017   |   Origin: Oasisbr






Mild cognitive impairment (part 1): Clinical characteristics and predictors of ...

Forlenza, Orestes V.; Diniz, Breno S.; Stella, Florindo [UNESP]; Teixeira, Antonio L.; Gattaz, Wagner F.

Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-27T11:28:48Z No. of bitstreams: 0Bitstream added on 2014-05-27T14:37:22Z : No. of bitstreams: 1 2-s2.0-84880978505.pdf: 119342 bytes, checksum: ae23d9006e3a83aa1a3157f552098c88 (MD5); Made available in DSpace on 2014-05-27T11:28:48Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-04-01; Objective: To critically review and...

Date: 2014   |   Origin: Oasisbr

Mild cognitive impairment (part 2): Biological markers for diagnosis and predic...

Forlenza, Orestes V.; Diniz, Breno S.; Teixeira, Antonio L.; Stella, Florindo [UNESP]; Gattaz, Wagner

Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-27T11:30:51Z No. of bitstreams: 0Bitstream added on 2014-05-27T14:49:01Z : No. of bitstreams: 1 2-s2.0-84885119225.pdf: 127761 bytes, checksum: 96b54a50835b7a2e10479942c817bc98 (MD5); Made available in DSpace on 2014-05-27T11:30:51Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-10-14; To present a critical review of pub...

Date: 2014   |   Origin: Oasisbr

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