11 documents found, page 1 of 2
Computational methods applied to syphilis: where are we, and where are we going?
Albuquerque, Gabriela; Fernandes, Felipe; Barbalho, Ingridy M. P.; Barros, Daniele M. S.; Morais, Philippi S. G.; Morais, Antônio H. F.Syphilis is an infectious disease that can be diagnosed and treated cheaply. Despite being a curable condition, the syphilis rate is increasing worldwide. In this sense, computational methods can analyze data and assist managers in formulating new public policies for preventing and controlling sexually transmitted infections (STIs). Computational techniques can integrate knowledge from experiences and, through ...
Unsupervised eeg preictal interval identification in patients with drug-resista...
Leal, Adriana; Curty, Juliana; Lopes, Fábio; Pinto, Mauro F.; Oliveira, Ana; Sales, Francisco; Bianchi, Anna M.; Ruano, Maria; Dourado, AntónioTypical seizure prediction models aim at discriminating interictal brain activity from pre-seizure electrographic patterns. Given the lack of a preictal clinical definition, a fixed interval is widely used to develop these models. Recent studies reporting preictal interval selection among a range of fixed intervals show inter- and intra-patient preictal interval variability, possibly reflecting the heterogeneit...
Development of technologies to support the diagnosis of infectious diseases and...
Ferreira, Matheus A. C.; Carvalho, Dionísio D. A.; Cruz, Agnaldo S.; Coutinho, Karilany D.; Oliveira, Carlos A. P.; Morais, Antonio H. F.Purpose Primary Health Care (PHC) is the coordinator of health care in Brazil and needs to be strengthened in the diagnostic field to increase health care quality. Aiming to improve the diagnostic tools currently available in PHC, this work describes the process of development and validation of two point-of-care biomedical devices for screening patients with syphilis or different kinds of cancer. Methods The de...
On the accuracy of code complexity metrics: A neuroscience-based guideline for ...
Hao, Gao; Hijazi, Haytham; Durães, João; Medeiros, Julio; Couceiro, Ricardo; Lam, Chan Tong; Teixeira, César A.; Castelhano, JoãoComplexity is the key element of software quality. This article investigates the problem of measuring code complexity and discusses the results of a controlled experiment to compare different views and methods to measure code complexity. Participants (27 programmers) were asked to read and (try to) understand a set of programs, while the complexity of such programs is assessed through different methods and pers...
On the clinical acceptance of black-box systems for EEG seizure prediction
Pinto, Mauro F.; Leal, Adriana Costa; Lopes, Fábio; Pais, José; Dourado, António; Sales, Francisco; Martins, Pedro; Teixeira, César A.Seizure prediction may be the solution for epileptic patients whose drugs and surgery do not control seizures. Despite 46 years of research, few devices/systems underwent clinical trials and/or are commercialized, where the most recent state-of- the- art approaches, as neural networks models, are not used to their full potential. The latter demonstrates the existence of social barriers to new methodologies due ...
Interpretable EEG seizure prediction using a multiobjective evolutionary algorithm
Pinto, Mauro F.; Coelho, Tiago; Leal, Adriana; Lopes, Fábio; Dourado, António; Martins, Pedro; Teixeira, César A.Seizure prediction might be the solution to tackle the apparent unpredictability of seizures in patients with drug-resistant epilepsy, which comprise about a third of all patients with epilepsy. Designing seizure prediction models involves defining the pre-ictal period, a transition stage between interictal brain activity and the seizure discharge. This period is typically a fixed interval, with some recent stu...
A personalized and evolutionary algorithm for interpretable EEG epilepsy seizur...
Pinto, Mauro F.; Leal, Adriana; Lopes, Fábio; Dourado, António; Martins, Pedro; Teixeira, César A.Seizure prediction may improve the quality of life of patients suffering from drug-resistant epilepsy, which accounts for about 30% of the total epileptic patients. The pre-ictal period determination, characterized by a transitional stage between normal brain activity and seizure, is a critical step. Past approaches failed to attain real-world applicability due to lack of generalization capacity. More recently,...
Heart rate variability analysis for the identification of the preictal interval...
Leal, Adriana; Pinto, Mauro F.; Lopes, Fábio; Bianchi, Anna M; Henriques, Jorge; Ruano, Maria G.; Carvalho, Paulo de; Dourado, AntónioElectrocardiogram (ECG) recordings, lasting hours before epileptic seizures, have been studied in the search for evidence of the existence of a preictal interval that follows a normal ECG trace and precedes the seizure's clinical manifestation. The preictal interval has not yet been clinically parametrized. Furthermore, the duration of this interval varies for seizures both among patients and from the same pati...
National registry for amyotrophic lateral sclerosis: a systematic review for st...
Barbalho, Ingridy; Valentim, Ricardo; Júnior, Mário Dourado; Barros, Daniele; Júnior, Hércules Pedrosa; Fernandes, Felipe; Teixeira, César A.Background: This article comprises a systematic review of the literature that aims at researching and analyzing the frequently applied guidelines for structuring national databases of epidemiological surveillance for motor neuron diseases, especially Amyotrophic Lateral Sclerosis (ALS). Methods: We searched for articles published from January 2015 to September 2019 on online databases as PubMed - U.S. National ...
Heart rate variability analysis for the identification of the preictal interval...
Leal, Adriana; Pinto, Mauro F.; Lopes, Fábio; Bianchi, Anna M.; Henriques, Jorge; Ruano, Maria; de Carvalho, Paulo; Dourado, António; Teixeira, César A.Electrocardiogram (ECG) recordings, lasting hours before epileptic seizures, have been studied in the search for evidence of the existence of a preictal interval that follows a normal ECG trace and precedes the seizure's clinical manifestation. The preictal interval has not yet been clinically parametrized. Furthermore, the duration of this interval varies for seizures both among patients and from the same pati...