8 documents found, page 1 of 1
Azole resistance in Candida albicans from animals: Highlights on efflux pump ac...
Rocha, Marcos Fábio Gadelha; Bandeira, Silviane Praciano; Alencar, Lucas Pereira de; Melo, Luciana Magalhães; Sales, Jamille AlencarThis study investigated potential mechanisms of azole resistance among Candida albicans from animals, including efflux pump activity, ergosterol content and gene expression. For this purpose, 30 azole-resistant C. albicans strains from animals were tested for their antifungal susceptibility, according to document M27-A3, efflux pump activity by rhodamine 6G test, ergosterol content and expression of the genes C...
Atividade da molécula tirosol, vancomicina e antibióticos beta-lactâmicos sobre...
Teixeira, Carlos Eduardo CordeiroDiversos são os relatos de resistência in vitro de cepas de Candida spp a fármacos antifúngicos, em especial a derivados azólicos A produção de biofilme é um importante fator de virulência e traz grandes repercussões clínica devido ao aumento da resistência à terapia antifúngica Deste modo a prospecção de novos compostos com propriedade antifúngica se faz necessária Alguns estudos têm evidenciado a atividade da...
Detection of Candida species resistant to azoles in the microbiota of rheas (Rh...
Brilhante, Raimunda Sâmia Nogueira; Alencar, Lucas Pereira de; Cordeiro, Rossana de Aguiar; Castelo-Branco, Débora de Souza Collares MaiaThere is growing interest in breeding rheas (Rhea americana) in Brazil. However, there are no data on the yeast microbiota of the gastrointestinal tract of this avian species, and the phenotypic characteristics of these yeasts are not known. Therefore, the aim of this work was to isolate Candida species from the digestive tract of rheas and to evaluate the in vitro antifungal susceptibility and secretion of pho...
Efeito do farnesol sobre o fenótipo de resistência e a produção de fosfolipase ...
Teixeira, Carlos Eduardo CordeiroThere are several reports of in vitro resistance to antifungal drugs, especially azole derivatives, in strains of Candida spp. For this reason, the pursuit for new compounds that present antifungal properties is necessary. Thus, this study aimed at evaluating the antifungal activity of farnesol and its interaction with classical antifungal drugs against Candida spp., as well as evaluating its effect on the prod...
Farnesol inhibits in vitro growth of the Cryptococcus neoformans species comple...
Cordeiro, Rossana de Aguiar; Nogueira, George Cândido; Brilhante, Raimunda Sâmia Nogueira; Teixeira, Carlos Eduardo Cordeiro; Mourão, Charles IelpoFarnesol is a sesquiterpene alcohol that modulates cell-to-cell communication in Candida albicans. In recent years, several studies have shown that this molecule presents inhibitory effects against non-albicans Candida species, Paracoccidioides brasiliensis and bacteria. The present study aimed at determining the effect of farnesol on the growth of strains of the Cryptococcus neoformans species complex, through...
Yeasts from Macrobrachium amazonicum : a focus on antifungal susceptibilityand ...
Brilhante, Raimunda Sâmia Nogueira; Paiva, Manoel de Araújo Neto; Sampaio, Célia M.S.; Teixeira, Carlos Eduardo CordeiroIn the present study, it was sought to compare yeast microbiota of wild and captive Macrobrachium amazonicum and evaluate the antifungal susceptibility and production of virulence factors by the recovered isolates of Candida spp. Additionally, cultivation water was monitored for the presence of fungi. Overall, 26 yeast isolates belonging to three genera and seven species were obtained, out of which 24 were Cand...
Glucose and lactose as cryoprotectants for fungal strains immobilised in sodium...
Rocha, Marcos Fábio Gadelha; Lima, Daniel Teixeira; Brilhante, Raimunda Sâmia Nogueira; Cordeiro, Rossana de Aguiar; Monteiro, Andre JallesThis research aimed at investigating the cryoprotectant action of glucose and lactose on strains of Malassezia spp. and zygomycetes immobilised in sodium alginate. Twelve strains of Malassezia spp. (nine M. furfur, two M. globosa and one M. sympodialis) and 12 zygomycetes (five Rhizopus oryzae and seven Mucor hiemales) were immobilised in sodium alginate, within plastic beads, maintained in appropriate media co...
Extratos de Moringa oleifera e Vernonia sp. sobre Candida albicans e Microsporu...
Rocha, Marcos Fábio Gadelha; Aguiar, Franscisco Léo Nascimento de; Brilhante, Raimunda Sâmia Nogueira; Cordeiro, Rossana de AguiarThe increase in the incidence of fungal infections and the frequent report of resistance and therapeutic failure has promoted the performance of phytochemical screening for compounds with antifungal properties. Based on this, the present study investigated the antifungal potential of extracts of Baccharis ligustrina, B. schultzii, Croton jacobinensis, Licania rigida, Moringa oleifera, Vernonia sp. and V. brasil...