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Synthesis, computational and nanoencapsulation studies on eugenol-derived insec...

Coelho, Catarina M. M.; Pereira, Renato B.; Vieira, Tatiana F.; Teixeira, Cláudia M.; Fernandes, Maria José Gomes; Rodrigues, Ana Rita O.

A new set of alkoxy alcohols were synthesised by reaction of eugenol oxirane with aliphatic and aromatic alcohols. These eugenol derivatives were evaluated against their effect upon the viability of the insect cell line Sf9 (Spodoptera frugiperda). The most promising compounds, 4-(3-(tert-butoxy)-2-hydroxypropyl)-2-methoxyphenol and 4-(2-((4-fluorobenzyl)oxy)-3-hydroxypropyl)-2-methoxyphenol were submitted to i...


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