29 documents found, page 1 of 3

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Cirurgia de nistagmo para correção da posição da cabeça: a propósito de 2 casos...

Lino, Pedro Miguel; Bastos, Mariana; Teixeira, Filipa; Capelas, Inês; Macedo, Dina; Mota, Armandina; Lázaro, Tiago; Silva, Laura

O nistagmo congénito é uma alteração do movimento ocular caracterizado por oscilações involuntárias. Pacientes com nistagmo congénito frequentemente viram a cabeça para colocar os olhos numa direção de fixação com o menor nistagmo, conhecida como "zona nula“ ou “posição de bloqueio”. Crianças com nistagmo congénito tendem a preferir olhar na direção da zona nula para alcançar a acuidade visual (AV) ideal. Quand...


Development of an in vitro skin cell model and comparison with ex vivo models: ...

Marques, Mariana; Teixeira, Filipa; Vieira, Mónica; Rodrigues, Francisca; Vieira, Mónica

Skin is the first physical barrier against pathogens and mechanical injuries, and stratum corneum, the outermost layer of the skin, is the primary barrier to therapeutic delivery. Skin is divided into the epidermis, which consists mainly of keratinocytes and the dermis, composed of fibroblasts, and extracellular matrix components. Skin models are crucial for assessing the safety and efficacy of cosmetic ingredi...


Unraveling the nutraceutical potential of Salicornia ramosissima by-product – i...

Pinto, Diana; Santos, Inês; Delerue-Matos, Cristina; Teixeira, Filipa; Sut, Stefania; Dall’Acqua, Stefano; Vieira, Mónica; Rodrigues, Francisca

Salicornia ramosissima by-product (SP) is an underexploited antioxidant-rich by-product. This study explored the phytochemical profile, bioaccessibility, and biological activity of SP before and after extraction (SBE and SAE, respectively) upon gastrointestinal simulated digestion and intestinal permeability. The phenolic and flavonoid concentrations increased during digestion, reaching bioaccessibility rates a...


Unlocking the functional potential of Mesembryanthemum nodiflorum: Insights int...

Pinto, Diana; Vieira, Raquel; Teixeira, Filipa; Sut, Stefania; Vieira, Mónica; Salazar, Miguel; Delerue-Matos, Cristina; Dall’Acqua, Stefano

Mesembryanthemum nodiflorum, commonly known as slenderleaf iceplant, is an undervalued edible halophyte. The nutraceutical potential of M. nodiflorum was investigated in the current study by extracting bioactive compounds using ultrasound-assisted extraction (UAE) and assessing the influence of gastrointestinal digestion and intestinal permeability on their bioactive composition. The phenolic and flavonoid cont...


Ultrasound-assisted extraction of bioactive compounds from goji berries: optimi...

Teixeira, Filipa; Silva, Ana Margarida; Sut, Stefania; Dall'Acqua, Stefano; Ramos, Oscar L.; Ribeiro, Alessandra B.; Ferraz, Ricardo

Lycium barbarum L. berries have a remarkable chemical composition and extensive biological activities, being a valuable component of health and nutraceutical practices. Nevertheless, a deep insight on the intestinal permeation of the pro-healthy bioactive compounds is urgently needed to predict the real effects on human body. This study attempted, for the first time, to optimize the Ultrasound-Assisted Extracti...


Insights into the bioactive composition, antioxidant properties and In vitro ce...

Silva, Ana Margarida; Moreira, Manuela M.; Teixeira, Filipa; Delerue-Matos, Cristina; Rodrigues, Francisca; Ferraz, Ricardo; Salazar, Miguel

Disphyma crassifolium, commonly known as sea fingers, is a halophyte plant recently introduced in gourmet cuisine. The present study aims to extract the bioactive compounds of D. crassifolium using ultrasound-assisted extraction and employing green solvents (water and ethanol). The antioxidant/antiradical activities, scavenging capacity against reactive species, phenolic profile, and intestinal effects were eva...


Ultrasound-assisted extraction of bioactive compounds from goji berries: Optimi...

Teixeira, Filipa; Silva, Ana Margarida; Sut, Stefania; Dall’Acqua, Stefano; Ramos, Oscar L.; Ribeiro, Alessandra B.; Ferraz, Ricardo

valuable component of health and nutraceutical practices. Nevertheless, a deep insight on the intestinal permeation of the pro-healthy bioactive compounds is urgently needed to predict the real effects on human body. This study attempted, for the first time, to optimize the Ultrasound-Assisted Extraction (UAE) of goji berries using a Response Surface Methodology approach and establish the intestinal permeation ...


Goji berries (Lycium barbarum) extract as new potential cosmetic ingredient – A...

Silva, Joana; Teixeira, Filipa; Silva, Ana M.; Vieira, Mónica; Amaral, M. Helena; Rodrigues, Francisca; Vieira, Mónica

Currently there is greater concern about appearance and skin care products. Although cosmetic products are not associated with serious health problems, there are concerns related to undesirable effects due to the presence of potentially carcinogenic and allergenic ingredients. Thus, consumers have been increasingly looking for products of natural and plant-based origin. The use of these products is expected to ...


Professional reintegration among professionally active Portuguese stroke surviv...

Matos, Joana; Moura, Ana; Teixeira, Filipa; Henriques, Ana; Alves, Elisabete

Purpose To assess professional reintegration, the perceived impact of stroke on work, and the main determinants of return to work (RTW) among stroke survivors. Materials and methods A cross-sectional study was performed, based on a cohort of stroke survivors. A structured questionnaire was administered to previously working stroke survivors, 18–24 months post-stroke. Data on sociodemographic characteristics, st...


A mixed-methods study protocol on the psychosocial health of stroke survivors a...

Moura, Ana; Teixeira, Filipa; Nogueira, Conceição; Henriques, Ana; de Freitas, Cláudia; Alves, Elisabete

Introduction: Surviving a stroke and caring for a survivor, impacts individuals’ psychological health and quality of life, which may impose substantial costs on healthcare and social systems. This study aims to understand and explore the psychological health, experiences, needs and quality of life of Portuguese stroke survivors and their informal carers. Methods and analysis: This is a mixed-methods, observatio...


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