Thyroid cancer integrates subtypes that are involved in signaling pathways that result in biological activities, such as differentiation, proliferation, in the absence of disease, and cell survival. BRAF is a gene that encodes the protein kinase\threonine that integrates the MAPK\ERK signaling pathway, as RAF signals are activated by the MAPK\ERK kinase and activates ERK\receptors. The current integrative revie...
Made available in DSpace on 2021-06-25T10:29:49Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-03-01; Objective: Choosing Wisely (CW) is an initiative that aims to advance the dialogue between physicians and patients about low-value health interventions. Given that thyroid conditions are frequent in clinical practice, we aimed to develop an evidence-based list of thyroid CW recommendations. Materials an...
Orientador: Ralff Ribeiro; Tese (doutorado) - Universidade Federal do Paraná, Setor de Ciências da Saúde, Programa de Pós-Graduação em Medicina Interna; Resumo: O receptor do hormônio tireoideano (TR) e o receptor do retinoide X (RXR) fazem parte de uma superfamília de receptores nucleares, que em resposta aos seus respectivos ligantes, atuam como fatores de transcrição no DNA. Os receptores nucleares possuem u...
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Submitted by Guilherme Lemeszenski (guilherme@nead.unesp.br) on 2013-08-22T19:04:35Z No. of bitstreams: 1 S0004-27302013000300006.pdf: 228940 bytes, checksum: e00ee3bcdf0c90f9ee85aefe477034ac (MD5); Made available in DSpace on 2013-08-22T19:04:35Z (GMT). No. of bitstreams: 1 S0004-27302013000300006.pdf: 228940 bytes, checksum: e00ee3bcdf0c90f9ee85aefe477034ac (MD5) Previous issue date: 2013-04-01; Made availabl...
Dietary fibers are defined as the component of the plants or analog carbohydrates that are resistant to digestion and absorption in the human small bowel. The America Dietetic Association recommends an ingestion of 20-30g of fiber per day. Evidences suggest that a diet rich in fibers brings benefits to health maintenance, by reducing the risk and the time of treatment of chronic diseases such as obesity, cardio...