52 documents found, page 1 of 6
Effect of individual's characteristics on volatile organic compoounds profile a...
Slezakova, Klara; Cavaleiro-Rufo, J.; Esteves, F.; Costa, D.; Pereira, M.C.; Teixeira, J.P.; Madureira, J.Breath analysis using an electronic nose (eNose) is a technology for exhaled volatile organic compounds (VOCs) that has shown potential in the diagnosis of respiratory diseases. However, the effect of an individual’s characteristics in the exhaled VOCs profile is far from fully understood. This pilot study aimed to identify the relevant characteristics of participants that may influence the VOCs profiles by the...
Impact of renovations on EDC levels and school children's health: bridging scie...
Hatem, G.; Salamova, A.; Haninnen, O.; Faria, A.M.; Costa, C.; Slezakova, K.; Teixeira, J.P.; Madureira, J.Building renovations may yield emissions of various air chemicals that can disrupt normal human endocrine functions. However, only a few endocrine disruptive health outcomes (e.g., respiratory, behavioural, or learning domains) have been comprehensively addressed among susceptible populations, particularly schoolchildren. This project investigates the role of school building renovations on childrenís exposure t...
Viability assay and DNA double strand break induction in nervous system cells e...
Fernandez-Bertolez, N.; Touzani, A.; Martinez, L.; Méndez, J.; Ramos-Paz, L.; Reis, A.T.; Fraga, S.; Costa, C.; Teixeira, J.P.; Pásaro, E.Cerium dioxide nanoparticles (CeO2 NP) show antioxidant enzyme mimetic properties and free radical scavenging activity. These properties make them a promising material for biomedical applications, but their potential adverse effects are not totally understood yet. Our objective was to assess the biological behaviour of CeO2 NP in human neuronal and glial cells. After carrying out the physical-chemical character...
Unveiling the potential of Thymus × citriodorus (Pers.) Schreb. preparations fo...
Oliveira, A.S.; Rolo, J.; Gaspar, C.; Cavaleiro, C.; Salgueiro, L.; Palmeira-de-Oliveira, R.; Ferraz, C.; Coelho, S.; Pastorinho, M, RamiroEthnopharmacological relevance Thymus × citriodorus (Pers.) Schreb. is an interspecific hybrid between Thymus pulegioides and Thymus vulgaris, known for its pharmacological activities as diaphoretic, deodorant, antiseptic and disinfectant, the last mostly related with its antimicrobial activity. The folk use of other extracts, as hydrolates, have also been disseminated, as regulators of oily skin with anti-acne...
Utility of salivary leucocytes for biomonitoring of human exposure to nanomater...
Valdiglesias, Vanessa; Fernández-Bertólez, Natália; Touzani, A.; Mendéz, J.; Martinez, L.; Pásaro, E.; Reis, A.T.; Fraga, S.; Teixeira, J.P.; Costa, C.Metal-based nanoparticles (NP) are being increasingly used in a wide variety of applications in consumer products and biomedical practices. As a result, human exposure to these nanomaterials is frequent, becoming a concern to public health. Human salivary leucocytes have been proposed as a proper biological sample for the comet assay, becoming an adequate non-invasive alternative model to evaluate DNA damage. I...
Indoor levels and health risk assessment of volatile organic compounds in Portu...
Slezakova, K.; Costa, C.; Valongo, C.; Teixeira, J.P.; Madureira, J.About indoor levels and health risk assessment of volatile organic compounds in Portuguese homes.
Issue 1 - “Update on adverse respiratory effects of outdoor air pollution” Part...
Sousa, A.C.; Pastorinho, M.R.; Masjedi, M.R.; Urrutia-Pereira, M.; Arrais, M.; Nunes, E.; To, T.; Ferreira, A.J.; Robalo-Cordeiro, C.; Borrego, C.Objective: To analyse the GARD perspective on the health effects of outdoor air pollution, and to synthesise the Portuguese epidemiological contribution to knowledge on its respiratory impact. Results: Ambient air pollution has deleterious respiratory effects which are more apparent in larger, densely populated and industrialised countries, such as Canada, Iran, Brazil and Portugal, but it also affects people l...
In vitro toxicity of metal nanoparticles in two human barrier models: role of t...
Pires, J; Moreira, L; Teixeira, J.P.; Fraga, S.Metal nanoparticles (M-NP) are among the most widely used nanomaterials in consumer products available in the market. Thus, human exposure to these nanosized materials is increasing, which raises serious concerns regarding their environmental and human safety. Biological barriers are important lines of defence to xenobiotics, thus expected targets for M-NP. The present study aimed at evaluating the in vitro tox...
In vitro toxicity assessment of paints with antimicrobial properties - a compar...
Machado-Querido, M.; Teixeira, J.P.; Pereira, C. CostaIn this work, the in vitro cytotoxicity of self-disinfecting wall paints containing antimicrobial substances was assessed, using skin and lung cell lines.
Insights into corrosion behaviour of uncoated Mg alloys for biomedical applicat...
Neves, C.S.; Sousa, I.; Freitas, M.A.; Moreira, L.; Costa, C.; Teixeira, J.P.; Fraga, S.; Pinto, E.; Almeida, A.; Scharnagl, N.; Zheludkevich, M.L.MgCa and MgGd series of alloys are often reported as promising candidates for biomedical applications. In the present study, cytotoxicity and corrosion behavior of Mg1Ca and Mg10Gd alloys in different electrolytes (NaCl, PBS, MEM) have been investigated in order to make a direct comparison and understand the mechanisms behind their performance. Potentiodynamic polarization and electrochemical impedance spectros...