3 documents found, page 1 of 1
Smaug1 membrane-less organelles respond to AMPK and mTOR and affect mitochondri...
Fernández-Alvarez, Ana J.; Gabriela Thomas, María; Pascual, Malena L.; Habif, Martín; Pimentel, Jerónimo; Corbat, Agustín A.; Pessoa, JoãoSmaug is a conserved translational regulator that binds numerous mRNAs, including nuclear transcripts that encode mitochondrial enzymes. Smaug orthologs form cytosolic membrane-less organelles (MLOs) in several organisms and cell types. We have performed single-molecule fluorescence in situ hybridization (FISH) assays that revealed that SDHB and UQCRC1 mRNAs associate with Smaug1 bodies in U2OS cells. Loss of f...
Detoxification of sewage sludge by natural attenuation and implications for its...
Mazzeo, Dânia Elisa Christofoletti [UNESP]; Casado, Marta; Piña, Benjamin; Marin-Morales, Maria Aparecida [UNESP]Made available in DSpace on 2018-12-11T16:48:53Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-12-01; Generalitat de Catalunya; Sewage Sludges (SS) from wastewater treatment systems constitute a potential alternative to agricultural fertilizers. However, their use is limited by the presence of toxic substances that may represent significant hazards for the environment and for human health. To test the p...
Retinoic acid receptors' expression and function during zebrafish early develop...
Oliveira, Eva; Casado, Marta; Raldúa, Demetrio; Soares, Amadeu; Barata, Carlos; Piña, BenjaminRetinoic acid (RA) regulates many developmental processes through its binding to two types of nuclear receptors, the retinoic acid receptor (RAR), and the retinoid-X receptor (RXR), which preferentially binds to the 9-cis isomer. Here we analyzed the RAR/RXR regulatory system during the first 5 days of development of zebrafish. Analysis of the relative transcript abundances for the four RAR and the six RXR zebr...