Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Micologia. Rio de Janeiro, RJ, Brasil.; Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Micologia. Rio de Janeiro, RJ, Brasil.; Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Micologia. Rio de Janeiro, RJ, Brasil.; Fundação Oswaldo Cruz. Inst...
Cryptococcus spp. are human pathogens that cause 181,000 deaths per year. In this work, we systematically investigated the virulence attributes of Cryptococcus spp. clinical isolates and correlated them with patient data to better understand cryptococcosis. We collected 66 C. neoformans and 19 C. gattii clinical isolates and analyzed multiple virulence phenotypes and host–pathogen interaction outcomes. C. neofo...
Made available in DSpace on 2021-06-25T10:50:15Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); National Institute of Allergy and Infectious Diseases; National Institutes of Health; National Institute of General Medical Sciences; Paracoccidioidomycosis is an endemic ...
Anopheles darlingi is the principal neotropical malaria vector, responsible for more than a million cases of malaria per year on the American continent. Anopheles darlingi diverged from the African and Asian malaria vectors ∼100 million years ago (mya) and successfully adapted to the New World environment. Here we present an annotated reference A. darlingi genome, sequenced from a wild population of males and f...
Made available in DSpace on 2018-11-26T17:42:05Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-09-01. Added 1 bitstream(s) on 2019-10-09T18:27:05Z : No. of bitstreams: 1 S0037-86822017000500715.pdf: 6017301 bytes, checksum: fed062c6fa6e089652cf2b7a9ad4b92a (MD5); Brazilian Society of Tropical Medicine and Hygiene; Brazilian Society of Infectology and Sociedade Paulista de Infectologia; Departamento de M...
Made available in DSpace on 2018-11-26T17:18:28Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-02-01. Added 1 bitstream(s) on 2019-10-09T18:26:29Z : No. of bitstreams: 1 S0074-02762017000200140.pdf: 1828179 bytes, checksum: 9f1a50aafd76094fae366ba0f3123567 (MD5); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); BACKGROUND...
Made available in DSpace on 2018-12-11T17:02:39Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-04-05; Background: Paracoccidioides brasiliensis and Paracoccidioides lutzii are the etiological agents of Paracoccidioidomycosis (PCM), and are easily isolated from human patients. However, due to human migration and a long latency period, clinical isolates do not reflect the spatial distribution of these pat...
Background: The fungal genus Sporothrix includes at least four human pathogenic species. One of these species, S. brasiliensis, is the causal agent of a major ongoing zoonotic outbreak of sporotrichosis in Brazil. Elsewhere, sapronoses are caused by S. schenckii and S. globosa. The major aims on this comparative genomic study are: 1) to explore the presence of virulence factors in S. schenckii and S. brasiliens...
Paracoccidioidomycosis (PCM) is a deep systemic mycosis caused by human fungal pathogens of the Paracoccidioides genus. The disease is geographically restricted to subtropical areas of Latin America (from south of Mexico to north of Argentina) with a high prevalence in Brazil, Colombia, Venezuela, and Argentina [1]. The annual incidence rate in Brazil is 10–30 infections per million inhabitants, and the mean mo...
Background: Paracoccidioides brasiliensis and Paracoccidioides lutzii are the etiological agents of Paracoccidioidomycosis (PCM), and are easily isolated from human patients. However, due to human migration and a long latency period, clinical isolates do not reflect the spatial distribution of these pathogens. Molecular detection of P. brasiliensis and P. lutzii from soil, as well as their isolation from wild a...