8 documents found, page 1 of 1
Artificial tendons' responsiveness to mechanical stress and biological performa...
Oliveira, Bruna; Teixeira, Marta O.; Gonçalves, Sónia P.; Ribeiro, Artur; Silva, C.; Felgueiras, Helena PradoHand tendon ruptures have increased due to mechanical stress, degeneration, trauma, and repetitive motion. This study proposes an artificial tendon engineered from polymeric braids made of lyocell, biodegradable polyester, and polyethylene terephthalate, functionalized with natural cork extract. Cork extract 2, obtained by cork powder using hydroethanolic solvent in a planetary mixture, exhibited a phenolic con...
NADES-in-Oil Emulsions Enriched with Essential Oils for Cosmetic Application
Freitas, David; Rocha, Diana; Santos, Joana; Noro, Jennifer Martins; Tavares, Tânia D.; Teixeira, Marta O.; Araújo, Daniela; Castro, Joana Isabel ReisThis research aims to explore the potential benefits of natural deep eutectic solvents (NADES) in formulating translucent NADES-in-oil emulsions (TEs) containing essential oils (EOs) for cosmetic applications. The TEs investigated in this study are based on previous formulations, consisting of 50 wt.% egg phosphatidylcholine (EPC), 20 wt.% ethanol, 20 wt.% olive oil (OlO), thyme oil (TO), or oregano oil (OrO), ...
Sodium alginate-based multifunctional sandwich-like system for treating wound i...
Ribeiro, Ana R. M.; Teixeira, Marta O.; Ribeiro, Lara; Tavares, Tânia Daniela Eugénio; Miranda, Catarina S.; Costa, André F.; Ribeiro, ArturMicrobial colonization and development of infections in wounds is a sign of chronicity. The prevailing approach to manage and treat these wounds involves dressings. However, these often fail in effectively addressing infections, as they struggle to both absorb exudates and maintain optimal local moisture. The system here presented was conceptualized with a three-layer design: the outer layer made of a fibrous p...
Developing translucent emulsions using sustainable NADES-based extracts
Freitas, David; Rocha, Diana; Santos, Joana; Noro, Jennifer Martins; Tavares, Tânia D.; Teixeira, Marta O.; Araújo, Daniela; Castro, JoanaIn this work, we explored natural deep eutectic solvents (NADES) for developing translucent NADES-in-oil emulsions (TEs) for cosmetic applications. NADES, composed of lactic acid and glycerol (1:1 and 1:4 ratios), were selected for their natural origin, non-toxicity, and compatibility with living organisms. These green solvents facilitated the extraction of bioactive compounds from Lavandula angustifolia, Corym...
Inhibition of Escherichia virus MS2, surrogate of SARS-CoV-2, via essential oil...
Domingues, Joana M.; Teixeira, Marta O.; Teixeira, Marta A.; Freitas, David; Silva, Samira F. da; Tohidi, Shafagh D.; Fernandes, Rui D. V.One of the most important measures implemented to reduce SARS-CoV-2 transmission has been the use of face masks. Yet, most mask options available in the market display a passive action against the virus, not actively compromising its viability. Here, we propose to overcome this limitation by incorporating antiviral essential oils (EOs) within polycaprolactone (PCL) electrospun fibrous mats to be used as interme...
Biodegradable wet-spun fibers modified with antimicrobial agents for potential ...
Felgueiras, Helena Prado; Homem, Natália Cândido; Teixeira, M. A.; Ribeiro, A. R. M.; Teixeira, Marta O.; Antunes, Joana Isabel CostaWet-spinning is a non-solvent induced phase inversion technique that allows the production of continuous polymeric microfibers, with a uniform morphology, based on the principle of precipitation. It allows the production of 3D fibrous constructs with an intricated architecture that facilitates cell infiltration, something that is very limited in electrospun nanofibrous mats, thus increasing its interest in biom...
Recent advances in fiber-hydrogel composites for wound healing and drug deliver...
Teixeira, Marta O.; Antunes, Joana Isabel Costa; Felgueiras, Helena PradoIn the last decades, much research has been done to fasten wound healing and target-direct drug delivery. Hydrogel-based scaffolds have been a recurrent solution in both cases, with some reaching already the market, even though their mechanical stability remains a challenge. To overcome this limitation, reinforcement of hydrogels with fibers has been explored. The structural resemblance of fiber–hydrogel compos...
Eugenol-containing essential oils loaded onto Chitosan/Polyvinyl alcohol blende...
Antunes, Joana Isabel Costa; Tavares, Tânia Daniela Eugénio; Ferreira, Marta Albertina Fernandes; Teixeira, Marta O.; Homem, Natália CândidoChronic wounds (CW) create numerous entryways for pathogen invasion and prosperity, further damaging host tissue and hindering its remodeling and repair. Essential oils (EOs) exert quick and efficient antimicrobial (AM) action, unlikely to induce bacterial resistance. Cinnamon leaf and clove oils (CLO and CO) display strong AM activity, namely against Staphylococcus aureus and Pseudomonas aeruginosa. Chitosan (...