10 documents found, page 1 of 1

The role of annexin A1 in the modulation of the NLRP3 inflammasome

Absence of CCR5 increases neutrophil recruitment in severe herpetic encephalitis

The neuroinflammatory response aimed at clearance of herpes simplex virus-1 (HSV-1) plays a key role in the pathogenesis of neuroaxonal damage in herpetic encephalitis. Leukocytes activated in an adaptive immune response access brain tissue by passing through the blood–brain barrier. The chemokine CCL5/RANTES is involved in recruitment of these cells to the brain acting via the receptors CCR1, CCR3 and mainly C...

Viral immunogenicity determines epidemiological fitness in a cohort of DENV-1 i...

Made available in DSpace on 2018-11-26T17:51:56Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-05-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); NIH/NIAID; The dynamics of dengue virus (DENV) circulation depends on serotype, genotype and lineage replacement and turnover. In Sao Jose do Rio Preto, Brazil, we observe...

Using adult Aedes aegypti females to predict areas at risk for dengue transmiss...

Made available in DSpace on 2018-12-11T16:52:02Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-06-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Introduction: Traditional indices for measuring dengue fever risk in a given area are based on the immature forms of the vector (larvae and pupae surveys). However, this is inefficient because only adult female mosquitoes actually transmit t...

Involvement of the chemokine RANTES (CCL5) in resistance to experimental infect...

The expression and putative role of chemokines during infection with Leishmania major in mice were investigated. CCL5 expression correlates with resistance, and blockade of CCL5 rendered mice more susceptible to infection. CCL5 is part of the cascade of events leading to efficient parasite control in L. major infection.

Therapeutic effects of treatment with anti-TLR2 and anti-TLR4 monoclonal antibo...

Brain natriuretic peptide based strategy to detect left ventricular dysfunction...

Background: Left ventricular dysfunction (LVd) is the main predictor of mortality in Chagas disease (ChD). Aims: To compare the diagnostic performance of the conventional approach (ECG and chest X-ray) in the recognition of LVd in ChD, with a new strategy, in which BNP is measured in patients with an abnormal ECG. Methods: Consecutive ChD patients recruited at an Outpatient Reference Center in Belo Horizonte, B...

In vivo inhibitory effect of anti-muscarinic autoantibodies on the parasympathe...

Deposição e uniformidade de distribuição da calda de aplicação em plantas de ca...

No âmbito da tecnologia de aplicação de agrotóxicos, a pulverização eletrostática é um sistema disponível comercialmente, no entanto, pouco empregado, devido à existência de algumas divergências quanto à efi ciência desse sistema, razão pela qual o entendimento dessa tecnologia e suas interações com a planta tornam-se necessários. Nesse contexto, objetivouse avaliar a utilização da pulverização eletrostática na...

Blockade of CXCR1/2 chemokine receptors protects against brain damage in ischem...

OBJECTIVE: Ischemic stroke may result from transient or permanent reductions of regional cerebral blood flow. Polymorphonuclear neutrophils have been described as the earliest inflammatory cells to arrive in ischemic tissue. CXCR1/2 receptors are involved in the recruitment of these cells. However, the contribution of these chemokine receptors during transient brain ischemia in mice remains poorly understood. I...