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Withanolides from Leaves of Nicandra physalodes

Carrero,Diego A. S.; Batista,Pedro H. J.; Souza,Luciana G. S.; Pinto,Francisco C. L.; Vasconcelos,Mayron A. de; Teixeira,Edson H.; Canuto,Kirley M.

Five new withanolides, designated as 15-oxo-nicaphysalin B, 6β,7α-dihydroxynicandrenone 10, 24α,25β-dihydroxy-nicandrenone-2 and a mixture of the epimers 17-(1α/1β-methylpropanone)-nicandrenone, in addition to six known others, were isolated from the leaf acetone extract from Nicandra physalodes. The complete structures of the five new withanolides, particularly their relative stereochemistries, were establishe...

Date: 2018   |   Origin: Oasisbr

Miscellaneous Diterpenes from the Aerial Parts of Plectranthus ornatus Codd

Ávila,Fábio N.; Pinto,Francisco C. L.; Sousa,Thiciana S.; Torres,Maria Conceição M.; Costa-Lotufo,Leticia V.; Rocha,Danilo D.; Vasconcelos,Mayron A. de

Five new diterpenes derivatives named as ornatin A, B, C, D and E, in addition to six known related diterpenes were isolated from the aerial parts of cultivated specimens of Plectranthus ornatus. The structures were elucidated using a combination of 1D/2D nuclear magnetic resonance (NMR) spectroscopy, high-resolution electrospray ionization mass spectrometry (HRESIMS) and comparison with published NMR data of a...

Date: 2017   |   Origin: Oasisbr

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