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Oxidative stress assessment in intestine of newborn rats submitted to hypoxia a...

Teixeira,Luciana Cristina; Fujiki,Renato Toshio Murashita; Souza,Caio Vinicius Coitinho Paiva de; Souza,Camila Mendes de; Mismetti,Maysa Moreira

Abstract Purpose: To evaluate the functional and structural response of tadalafil effects in the intestinal mucosa, using an experimental model of hypoxia and reoxygenation injury in rats. Methods: The animals were divided into 4 groups: CTL, H/R, H/R+Td and M+Td. The newborn rats allocated in groups H/R, H/R+Td and M+Td were submitted twice a day, to a gas chamber with CO2 at 100% for 10 minutes and afterward ...

Date: 2019   |   Origin: Oasisbr

Effect of folic acid in a modified experimental model of anorectal malformation...

Faria,Danilo José Fiorindo; Simões,Manuel de Jesus; Teixeira,Luciana Cristina; Faria,Angela Tucci Pinheiro; Cintra,Álvaro Edmundo Simões Ulhoa

PURPOSE: To determine the effect of a single dose of adriamycin (ADR) to induce anorectal malformations (ARMs) and determine the effect of folic acid (FA) in this model. METHODS: Ten female Wistar rats were divided randomly in two groups. Group A - ADR; Group B - FA+ADR. Dams from group B received daily, since two weeks before the pregnancy to the end of pregnancy, FA (50mg/kg) by gavage. Dams from both groups ...

Date: 2016   |   Origin: Oasisbr

Penile reconstruction using mesenchymal stem cells

Laks,Marcus; Freitas-Filho,Luiz Gonzaga; Sayeg,Kleber; Leite,Mila Torii Correia; Teixeira,Luciana Cristina

PURPOSE: To compare the reconstruction of corpus cavernosum segments when seeded with mesenchymal stem cells and when stem cells are infused intravenously.METHODS: Sixteen New Zealand rabbits were submitted to reconstruction of the corpus cavernosum and distributed in Group A - decellularized matrices, Group B - decellularized matrices seeded with mesenchymal stem cells Group C - decellularized matrices submitt...

Date: 2015   |   Origin: Oasisbr

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