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Influence of estrogen deficiency and tibolone therapy on trabecular and cortica...
Carvalho,Ana Carolina Bergmann de; Fernandes,Gustavo Vieira Oliveira; Lima,Inayá; Oliveira,Davi Ferreira de; Henriques,Helene NaraPURPOSE: To verify the effects of tibolone administration on trabecular and cortical bone of ovariectomized female rats by computed radiography system (CRS). METHODS: The experiment was performed on two groups of rats previously ovariectomized, one received tibolone (OVX+T) while the other did not (OVX), those groups were compared to a control group (C) not ovariectomized. Tibolone administration (1mg/day) bega...
Repair of critical-size defects with autogenous periosteum-derived cells combin...
Paulo,Anderson de Oliveira; Castro-Silva,Igor Iuco; Oliveira,Davi Ferreira de; Machado,Manoel Eduardo de Lima; Bonetti-Filho,IdomeoThe aim of this study was to evaluate the bone repair using autogenous periosteum-derived cells (PDC) and bovine anorganic apatite and collagen (HA-COL). PDC from Wistar rats (n=10) were seeded on HA-COL discs and subjected to osteoinduction during 6 days. Critical-size defects in rat calvarias were treated with blood clot (G1), autogenous bone (G2), HA-COL (G3) and HA-COL combined with PDC (G4) (n=40), and the...