5 documents found, page 1 of 1
Prevalence of hepatitis C virus in Brazil’s inmate population: a systematic review
Magri,Mariana Cavalheiro; Ibrahim,Karim Yaqub; Pinto,Walkyria Pereira; França,Francisco Oscar de Siqueira; Bernardo,Wanderley MarquesOBJECTIVE To estimate the prevalence of hepatitis C virus infection in Brazil’s inmate population.METHODS Systematic review on hepatitis C virus infection in the inmate population. Brazilian studies published from January 1, 1989 to February 20, 2014 were evaluated. The methodological quality of the studies was assessed using a scale of 0 to 8 points.RESULTS Eleven eligible studies were analyzed and provided da...
Hepatitis C: sexual or intrafamilial transmission? Epidemiological and phylogen...
Cavalheiro,Norma de Paula; De La Rosa,Abel; Elagin,Slava; Tengan,Fátima Mitiko; Araújo,Evaldo Stanislau Affonso de; Barone,Antonio AlciThe role of sexual or intrafamilial transmission of hepatitis C is controversial. A phylogenetic analysis was performed on the non-structural region 5B of the hepatitis C virus (NS5B-HCV). High percentages of homology (mean of 98.3%) were shown between the couples. Twenty (83.3%) of the 24 men but only two of the women (8.3%) reported having had sexually transmitted diseases during their lives. The risk factors...
Detection of HCV by PCR in serum and PBMC of patients with hepatitis C after tr...
Cavalheiro,Norma de Paula; Filgueiras,Thelma Cristina; Melo,Carlos Eduardo; Morimitsu,Suzana Rie; Araújo,Evaldo Stanislau Affonso deAlthough hepatitis C is mainly hepatotropic, some studies suggest that hepatitis C virus (HCV) infects peripheral blood mononuclear cells (PBMC), using them as a reservoir, which might contribute to the development of resistance to treatment. Fifty-four hepatitis-C patients, who had been submitted to treatment, were selected. Blood samples were collected on the same day for the detection of HCV RNA in serum and...
Fatores associados às formas evolutivas graves da infecção crônica pelo vírus d...
Vasconcelos,Romes Rufino de; Tengan,Fátima Mitiko; Cavalheiro,Norma de Paula; Ibrahim,Karim; Pereira,Hayde; Barone,Antonio AlciCom o objetivo de descrever os fatores epidemiológicos e clínicos-laboratoriais e avaliar os fatores associados ao desenvolvimento de fibrose moderada e grave, realizou-se a revisão de 426 prontuários médicos de pacientes com infecção crônica pelo vírus da hepatite C, atendidos na Clínica de Moléstias Infecciosas e Parasitárias da Faculdade de Medicina da Universidade de São Paulo, no período de 01/01 a 31/12/2...
Are anti-interferon antibodies the cause of failure in: chronic HCV hepatitis t...
Barone,Antonio Alci; Tosta,Rose Aparecida Borges; Tengan,Fátima Mitiko; Marins,José Humberto Caetano; Cavalheiro,Norma de Paula; Cardi,Bruno AndradeA follow-up study was made of 94 chronic hepatitis C patients at a hepatitis clinic in Brazil, after interferon alpha (IFN-alpha) therapy, to determine the influence of anti-interferon antibodies on treatment outcome. Patients diagnosed as having chronic hepatitis C, confirmed by PCR (HCV RNA) and liver biopsy, were treated with interferon alpha 2a or 2b for at least six months, and were followed up for 24 week...