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Murine glial protrusion transcripts predict localized Drosophila glial mRNAs in...

Lee, Jeffrey Y.; Gala, Dalia S.; Kiourlappou, Maria; Olivares-Abril, Julia; Joha, Jana; Titlow, Joshua S.; Teodoro, Rita; Davis, Ilan

Publisher Copyright: © 2024 Lee et al.; The polarization of cells often involves the transport of specific mRNAs and their localized translation in distal projections. Neurons and glia are both known to contain long cytoplasmic processes, while localized transcripts have only been studied extensively in neurons, not glia, especially in intact nervous systems. Here, we predict 1,740 localized Drosophila glial tr...


Drosophila motor neuron boutons remodel through membrane blebbing coupled with ...

Fernandes, Andreia R.; Martins, João P.; Gomes, Edgar R.; S. Mendes, César; Teodoro, Rita

Funding Information: We would like to thank Telmo Pereira from the Microscopy Facility for technical support, the Fly Facility at Nova Medical Research; CONGENTO: consortium for genetically tractable organisms. We thank the Developmental Studies Hybridoma Bank, Bloomington Drosophila Stock Center and VDRC for antibodies and fly stocks. This work was supported by PTDC-01778/2022- NeuroDev3D to R.O.T. GEMiNI and ...


Far from home

Gala, Dalia S.; Titlow, Joshua S.; Teodoro, Rita; Davis, Ilan

Funding: We thank Aino Järvelin and Jeffrey Y. Lee for help with the conceptualization and discussions of this review. This work was funded by a Wellcome Investigator Award 209412/Z/17/Z and Wellcome Strategic Awards (Micron Oxford) 091911/B/10/Z and 107457/Z/ 15/Z to I.D. D.S.G. is funded by Medial Sciences Graduate Studentships, University of Oxford. R.O.T. is funded by iNOVA4Health—UIDB/04462/2020 and EXPL/B...


Current methods to analyse lysosome morphology, positioning, motility and function

Barral, Duarte C.; Staiano, Leopoldo; Almeida C, Guimas; Cutler, Dan F; Eden, Emily R; Futter, Clare E; Galione, Antony; Marques, André R A

Funding: We thank Liliana Bento for valuable assistance in formatting the manuscript. This article was supported by the LYSOCIL project. This project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 811087. CGA has funding from Maratona da Saúde 2016 and Fundaçao para a Ciência e a Tecnologia ˜ , I.P. (CEECIND/00410/2017). FMP is a Wellcome I...


Overview of beneficial effects of (Poly)phenol metabolites in the context of ne...

Carregosa, Diogo; Mota, Sara; Ferreira, Sofia; Alves-Dias, Beatriz; Loncarevic-Vasiljkovic, Natasa; Crespo, Carolina Lage; Menezes, Regina

Funding Information: Funding: This work has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme under grant agreement No 804229. iNOVA4Health Research Unit (LISBOA—01–0145—FEDER—007344), which is cofunded by Fundação para a Ciência e Tecnologia (FCT)/Ministério da Ciência e do Ensino Superior, through national funds, and by FEDER un...


Peripheral axonal ensheathment is regulated by RalA GTPase and the exocyst complex

Silva-Rodrigues, Joana F.; Patrício-Rodrigues, Cátia F.; de Sousa-Xavier, Vicente; Augusto, Pedro M.; Fernandes, Ana C.; Farinho, Ana R.

Funding This work was supported by H2020 Marie Skłodowska-Curie Actions [H2020- GA661543-Neuronal Trafficking to R.O.T.], Fundo Regional para a Ciência e Tecnologia [IF/00392/2013/CP1192/CT0002 to R.O.T.] and iNOVA4Health (UID/Multi/04462/2013) (co-funded by FCT-FEDER-PT2020).; Axon ensheathment is fundamental for fast impulse conduction and the normal physiological functioning of the nervous system. Defects in...


Postsynaptic Rab GTPases and Exocyst: a screen at the Drosophila neuromuscular ...

Patrício-rodrigues, Cátia; Teodoro, Rita

Funding:This work was supported by H2020-GA661543-Neuronal Trafficking (ROT), IF/00392/2013/ CP1192/CT0002, FCT – Portugal (ROT) and by UID/Multi/04462/2013 from iNOVA4Health (co-fundend by FCT-FEDER-PT2020).


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