Made available in DSpace on 2022-04-28T17:22:32Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-10-01; Janssen Research & Development, LLC; Objectives. To assess efficacy, pharmacokinetics (PK) and safety of intravenous (i.v.) golimumab in patients with polyarticular-course JIA (pc-JIA). Methods. Children aged 2 to <18 years with active pc-JIA despite MTX therapy for >= 2months received 80 mg/m(2) golimu...
Made available in DSpace on 2022-04-29T08:46:47Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-12-01; Objective: To present an updated and evidence-based guideline for the use of dual-energy x-ray absorptiometry (DXA) to assess body composition in clinical practice. Materials and methods: This Official Position was developed by the Scientific Committee of the Brazilian Association of Bone Assessment and...
Made available in DSpace on 2022-04-29T08:30:48Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-10-01; Objectives: To assess efficacy, pharmacokinetics (PK) and safety of intravenous (i.v.) golimumab in patients with polyarticular-course JIA (pc-JIA). Methods: Children aged 2 to <18 years with active pc-JIA despite MTX therapy for ≥2 months received 80 mg/m2 golimumab at weeks 0, 4, then every 8 weeks th...
Background: Rheumatic diseases are associated with an increase in overall risks of tuberculosis (TB). The aim of this study was to evaluate the frequency of TB and the frequency of latent TB infection (LTBI), in clinical practice, for juvenile idiopathic arthritis (JIA) patients from high and low risk of TB incidence endemic countries. Methods: This is an international, multicenter, cross-sectional, observation...
Made available in DSpace on 2021-06-25T12:24:54Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-11-11; Background: Concerns about the safety and efficacy of vaccines in patients with autoimmune diseases (AID) have led to contradictions and low vaccination coverage in this population, who are at a higher risk of infections, including by human papillomavirus (HPV). Although HPV vaccines have been recommend...
Made available in DSpace on 2019-10-06T16:48:48Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-01-18. Added 1 bitstream(s) on 2021-07-15T15:23:52Z : No. of bitstreams: 1 S2523-31062019000100201.pdf: 819925 bytes, checksum: f22259d5ed182e513c252853fdb44c14 (MD5); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); OBJECTIVE: To evaluate prevalence, clinical manifestations, laboratory ab...
Made available in DSpace on 2018-11-26T17:42:33Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-11-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Federico Foundation; Nucleo de Apoio a Pesquisa Saude da Crianca e do Adolescente of USP (NAP-CriAd); Objectives: To assess clinical digital vasculitis (DV) as an initial manifestation of childhood onset systemic lupus erythematosus (...
Made available in DSpace on 2018-12-11T16:44:29Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-02-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); The aim of this study was to evaluate pulmonary hypertension (PH) in 852 childhood-onset systemic lupus erythematosus (cSLE) patients. This was a large multicenter study conducted in 10 Pediatric Rheumatology Services of São Paulo sta...
Made available in DSpace on 2018-12-11T17:22:56Z (GMT). No. of bitstreams: 0 Previous issue date: 2015-01-01; Background: Data regarding the prevalence of chronic spontaneous urticaria (CSU) in childhood-onset systemic lupus erythematosus (cSLE) patients and possible associated factors are limited to a few case reports. The objectives of this study were to assess CSU in a large cSLE population, in order to eval...