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Role of adenosine in epilepsy and seizures
Tescarollo, Fabio C.; Rombo, Diogo M.; DeLiberto, Lindsay K.; Fedele, Denise E.; Alharfoush, Enmar; Tomé, Ângelo R.; Cunha, Rodrigo A.; Sebastião, Ana MAdenosine is an endogenous anticonvulsant and neuroprotectant of the brain. Seizure activity produces large quantities of adenosine, and it is this seizure-induced adenosine surge that normally stops a seizure. However, within the context of epilepsy, adenosine plays a wide spectrum of different roles. It not only controls seizures (ictogenesis), but also plays a major role in processes that turn a normal brain...
Date: 2020
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Origin: Repositório da Universidade de Lisboa