3 documents found, page 1 of 1
Polyarthritis due to metastatic calcinosis in a patient with new WT1 gene mutat...
Martins, F. Rajão; Gonçalves, Francisco; Guedes, A.; Sequeira, G.; Ribeiro, C.Metastatic calcinosis is an uncommon condition characterized by diffuse soft tissue calcification, which may occur with advanced chronic kidney disease (CKD), typically in those undergoing kidney replacement therapy (1, 2). Deposits usually appear around large joints such as the elbow, hip, and shoulder. Periarticular deposits may lead to arthralgia, reduced joint mobility, and neurovascular symptoms. Sustained...
Neutrophile to lymphocyte and platelet to lymphocyte ratios predict clinical re...
Martins, F. Rajão; Bernardes, M.; Sequeira, G.; Costa, L.; Carvalho, P. DavidObjective: We aim to study association between neutrophile to lymphocyte (NLR) and platelet to lymphocyte (PLR) ratios and disease activity, and their value to predict bDMARD response. Methods: A set of spondylarthritis (SpA) patients under bDMARD registered in the Reuma.pt registry was studied. Sociodemographic, clinical and laboratorial variables were assessed on bDMARD initiation, 6, 12, 18 and 24 months (M)...
The GO-DACT is an investigator-initiated, national, multicentric randomized pla...
Vieira-Sousa, E; Canhão, H; Alves, P; Rodrigues, AM; Teixeira, F; Tavares-Costa, J; Bernardo, A; Pimenta, S; Pimentel-Santos, .; Gomes, JL; Aguiar, RThe GO-DACT is an investigator-initiated, national, multicentric randomized placebo-controlled double-blinded trial, that assesses dactylitis as primary endpoint. Psoriatic arthritis patients naïve to methotrexate and biologic disease modifying anti-rheumatic drugs, with at least one active dactylitis, were assigned to golimumab in combination with methotrexate or placebo in combination with methotrexate, for 2...