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Exploratory Data Analysis of Cell and Mitochondrial High-Fat, High-Sugar Toxici...

Amorim, Ricardo; Simões, Inês C. M.; Veloso, Caroline; Carvalho, Adriana; Simões, Rui F.; Pereira, Francisco B.; Thiel, Theresa; Normann, Andrea

Non-alcoholic steatohepatitis (NASH), one of the deleterious stages of non-alcoholic fatty liver disease, remains a significant cause of liver-related morbidity and mortality worldwide. In the current work, we used an exploratory data analysis to investigate time-dependent cellular and mitochondrial effects of different supra-physiological fatty acids (FA) overload strategies, in the presence or absence of fruc...


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