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Molecular cytogenetic pilot study on pleomorphic adenomas of salivary glands

Thielker, Jovanna; Weise, Anja; Othman, Moneeb A. K.; Carreira, Isabel M.; Melo, Joana B.; Von Eggeling, Ferdinand; Guntinas-Lichius, Orlando

Pleomorphic adenomas (PAs) of salivary glands are the most frequent entity of solid parotid tumors. Nonetheless, their genetics is not yet well understood. Thus, the current study characterized 14 PAs using a unique combination of cytogenetic, molecular cytogenetic and/or molecular karyotyping based approaches. The current study applied G-banding based on trypsin treatment and Giemsa-staining in peripheral bloo...

Date: 2020   |   Origin: Estudo Geral - Universidade de Coimbra
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