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Minimizing Errors in RT-PCR Detection and Quantification of SARS-CoV-2 RNA for ...

Ahmed, Warish; Simpson, Stuart; Bertsch, Paul; Bibby, Kyle; Bivins, Aaron; Blackall, Linda; Bofill-Mas, Silvia; Bosch, Albert; Brandao, Joao; Choi, Phil

Wastewater surveillance for pathogens using the reverse transcription-polymerase chain reaction (RT-PCR) is an effective, resource-efficient tool for gathering additional community-level public health information, including the incidence and/or prevalence and trends of coronavirus disease-19 (COVID-19). Surveillance of SARS-CoV-2 in wastewater may provide an early-warning signal of COVID-19 infections in a comm...


Multi-year inter-laboratory exercises for the analysis of illicit drugs and met...

van Nuijs, Alexander L.N.; Lai, Foon Yin; Been, Frederic; Andres-Costa, Maria Jesus; Barron, Leon; Baz-Lomba, Jose Antonio; Berset, Jean-Daniel

This study presents the development of a worldwide inter-laboratory testing scheme for the analysis of seven illicit drug residues in different matrices (standard solutions, tap- and wastewater). By repeating this exercise for six years with participation of 37 laboratories from 25 countries, the testing scheme was substantially improved based on experiences gained across the years (e.g. matrix type, sample con...


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