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Management of patients at very high risk of osteoporotic fractures through sequ...

Curtis, Elizabeth M.; Reginster, Jean-Yves; Al-Daghri, Nasser; Biver, Emmanuel; Brandi, Maria Luisa; Cavalier, Etienne; Hadji, Peyman; Halbout, Philippe

Osteoporosis care has evolved markedly over the last 50 years, such that there are now an established clinical definition, validated methods of fracture risk assessment and a range of effective pharmacological agents. Currently, bone-forming (anabolic) agents, in many countries, are used in those patients who have continued to lose bone mineral density (BMD), patients with multiple subsequent fractures or those...


Environmental and societal factors associated with COVID-19-related death in pe...

Izadi, Zara; Gianfrancesco, Milena A.; Schmajuk, Gabriela; Jacobsohn, Lindsay; Katz, Patricia; Rush, Stephanie; Ja, Clairissa; Taylor, Tiffany

Background: Differences in the distribution of individual-level clinical risk factors across regions do not fully explain the observed global disparities in COVID-19 outcomes. We aimed to investigate the associations between environmental and societal factors and country-level variations in mortality attributed to COVID-19 among people with rheumatic disease globally. Methods: In this observational study, we de...


Role of vitamin D supplementation in the management of musculoskeletal diseases...

Chevalley, Thierry; Brandi, Maria Luisa; Cashman, Kevin D.; Cavalier, Etienne; Harvey, Nicholas C.; Maggi, Stefania; Cooper, Cyrus; Al-Daghri, Nasser

Vitamin D is a key component for optimal growth and for calcium-phosphate homeostasis. Skin photosynthesis is the main source of vitamin D. Limited sun exposure and insufficient dietary vitamin D supply justify vitamin D supplementation in certain age groups. In older adults, recommended doses for vitamin D supplementation vary between 200 and 2000 IU/day, to achieve a goal of circulating 25-hydroxyvitamin D (c...


Factors associated with COVID-19-related death in people with rheumatic disease...

Strangfeld, Anja; Schäfer, Martin; Gianfrancesco, Milena A.; Lawson-Tovey, Saskia; Liew, Jean W.; Ljung, Lotta; Mateus, Elsa F.; Richez, Christophe

Objectives: To determine factors associated with COVID-19-related death in people with rheumatic diseases. Methods: Physician-reported registry of adults with rheumatic disease and confirmed or presumptive COVID-19 (from 24 March to 1 July 2020). The primary outcome was COVID-19-related death. Age, sex, smoking status, comorbidities, rheumatic disease diagnosis, disease activity and medications were included as...


Revelando Hercule Florence, o Amigo das Artes: análises por fluorescência de ra...

Rizzutto, Márcia de Almeida; Lee, Francis Melvin; Thomas, Thierry

Os debates sobre o pioneirismo de Hercule Florence (Nice, França, 1804 – Campinas, SP, 1879) na descoberta do processo fotográfico basearam-se, principalmente, em seus manuscritos, uma vez que poucas de suas épreuves photographiques (experiências fotográficas) sobreviveram. Os avanços tecnológicos das últimas quatro décadas permitiram que em 2016 alguns destes exemplares de impressions à la lumière solaire foss...

Date: 2019   |   Origin: Oasisbr

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