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Association of statin use on survival outcomes of patients with early-stage HER...

Maurer, Christian; Agostinetto, Elisa; Ameye, Lieveke; Lambertini, Matteo; Martel, Samuel; Ponde, Noam; Brandão, Mariana; Poggio, Francesca

Purpose There is evidence that statins might improve the outcome of patients with breast cancer. The role of statins in patients with early HER2-positive breast cancer is unknown. Therefore, we explored the association between statin use and survival outcomes in early HER2-positive breast cancer patients in the phase III APHINITY trial (adjuvant pertuzumab/ trastuzumab). Methods All patients (intent-to-treat po...


6th and 7th International consensus guidelines for the management of advanced b...

Cardoso, Fatima; Paluch-Shimon, Shani; Schumacher-Wulf, Eva; Matos, Leonor; Gelmon, Karen; Aapro, Matti S.; Bajpai, Jyoti; Barrios, Carlos H.

This manuscript describes the Advanced Breast Cancer (ABC) international consensus guidelines updated at the last two ABC international consensus conferences (ABC 6 in 2021, virtual, and ABC 7 in 2023, in Lisbon, Portugal), organized by the ABC Global Alliance. It provides the main recommendations on how to best manage patients with advanced breast cancer (inoperable locally advanced or metastatic), of all brea...


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