<p><b>OBJECTIVE:</b> To evaluate the impact of age in health-related quality of life (HRQoL) in older adults with cancer.<br> <b>METHODS:</b> This was a cross-sectional study of 608 older adults diagnosed with cancer. Age groups were considered an independent variable. For the analysis of HRQoL, the mean scores of age groups were compared by analysis of variance and the Scheffé comparison test. For measuring th...