2 documents found, page 1 of 1
Managing severe tuberculosis and its sequelae: from intensive care to surgery a...
Tiberi,Simon; Torrico,Marcela Muñoz; Rahman,Ananna; Krutikov,Maria; Visca,Dina; Silva,Denise Rossato; Kunst,Heinke; Migliori,Giovanni BattistaABSTRACT Multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) continue to challenge physicians and public health specialists. Global treatment outcomes continue to be unsatisfactory, positive outcomes being achieved in only 54% of patients. Overall outcomes are even worse in patients infected with highly resistant strains. Treating MDR-/XDR-TB is difficult because of fr...
New and repurposed drugs to treat multidrug- and extensively drug-resistant tub...
Silva,Denise Rossato; Dalcolmo,Margareth; Tiberi,Simon; Arbex,Marcos Abdo; Munoz-Torrico,Marcela; Duarte,Raquel; D’Ambrosio,Lia; Visca,DinaABSTRACT Multidrug-resistant and extensively drug-resistant tuberculosis (MDR-TB and XDR-TB, respectively) continue to represent a challenge for clinicians and public health authorities. Unfortunately, although there have been encouraging reports of higher success rates, the overall rate of favorable outcomes of M/XDR-TB treatment is only 54%, or much lower when the spectrum of drug resistance is beyond that of...