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Population structure and history of Mycobacterium bovis European 3 clonal compl...
Pereira, André C.; Lourenço, José; Themudo, Gonçalo; Botelho, Ana; Cunha, Mónica V.Mycobacterium bovis causes animal tuberculosis in livestock and wildlife, with an impact on animal health and production, wildlife management, and public health. In this work, we sampled a multi-host tuberculosis community from the official hotspot risk area of Portugal over 16 years, generating the largest available data set in the country. Using phylogenetic and ecological modeling, we aimed to reconstruct th...
Rescue of Mycobacterium bovis DNA Obtained from Cultured Samples during Officia...
Pinto, Daniela; Themudo, Gonçalo; Pereira, André C.; Botelho, Ana; Cunha, Mónica V.Epidemiological surveillance of animal tuberculosis (TB) based on whole genome sequencing (WGS) of Mycobacterium bovis has recently gained track due to its high resolution to identify infection sources, characterize the pathogen population structure, and facilitate contact tracing. However, the workflow from bacterial isolation to sequence data analysis has several technical challenges that may severely impact ...
Population structure and history of Mycobacterium bovis European 3 clonal compl...
Pereira, André C.; Lourenço, José; Themudo, Gonçalo; Botelho, Ana; Cunha, Mónica V.Mycobacterium bovis causes animal tuberculosis in livestock and wildlife, with an impact on animal health and production, wildlife management, and public health. In this work, we sampled a multi-host tuberculosis community from the official hotspot risk area of Portugal over 16 years, generating the largest available data set in the country. Using phylogenetic and ecological modeling, we aimed to reconstruct th...