OBJECTIVE: The main aim of the study was to evaluate the efficacy and safety profile of Nivolumab, an immune-checkpoint-inhibitor antibody, in advanced, previously treated, Non-Small Cell Lung Cancer (NSCLC) patients, in a real world setting. METHODS: We performed a retrospective, multicentre data analysis of patients who were included in the Portuguese Nivolumab Expanded Access Program (EAP). Eligibility crite...
Antemortem diagnosis of cardiac metastasis is rarely observed. A case of cardiac metastasis from colon adenocarcinoma is reported. The diagnosis of an intracavitary mass of the right atrium and vegetant mass of the tricuspid valve was possible by two dimensional transthoracic echocardiography. The authors make a brief reference to the clinical and imaging features of secondary cardiac tumors, with special empha...
We diagnosed a 20 year old young girl, with clinical and laboratorial evidence of pancytopenia, an acute megakaryoblastic leukemia. The difficulty in arriving at this conclusion was only surpassed with the help of monoclonal antibodies. With the presentation of this case we approach the problematics in obtaining the diagnostic of the megakaryoblastic leukemia. This is fundamental, owing to the possibilities of ...