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Adenosine A2A Receptors Control Glutamatergic Synaptic Plasticity in Fast Spiki...
Kerkhofs, Amber; Canas, Paula M.; Timmerman, A. J.; Heistek, Tim S.; Real, Joana I.; Xavier, Carolina; Cunha, Rodrigo A.; Mansvelder, Huibert D.Adenosine A2A receptors (A2AR) are activated upon increased synaptic activity to assist in the implementation of long-term plastic changes at synapses. While it is reported that A2AR are involved in the control of prefrontal cortex (PFC)-dependent behavior such as working memory, reversal learning and effort-based decision making, it is not known whether A2AR control glutamatergic synapse plasticity within the ...
Date: 2018
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Origin: Estudo Geral - Universidade de Coimbra