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The Sequential Organ Failure Assessment (SOFA) Score: Has the Time Come for an ...

Moreno, R; Rhodes, A; Piquilloud, L; Hernandez, G; Takala, J; Gershengorn, H; Tavares, M; Coopersmith, C; Myatra, S; Singer, M; Rezende, E; Prescott, H

The Sequential Organ Failure Assessment (SOFA) score was developed more than 25 years ago to provide a simple method of assessing and monitoring organ dysfunction in critically ill patients. Changes in clinical practice over the last few decades, with new interventions and a greater focus on non-invasive monitoring systems, mean it is time to update the SOFA score. As a first step in this process, we propose so...


The Intensive Care Global Study on Severe Acute Respiratory Infection (IC-GLOSS...

Sakr, Y; Ferrer, R; Reinhart, K; Beale, R; Rhodes, A; Moreno, R; Timsit, JF; Brochard, L; Thompson, BT; Rezende, E; Chiche, JD

PURPOSE: In this prospective, multicenter, 14-day inception cohort study, we investigated the epidemiology, patterns of infections, and outcome in patients admitted to the intensive care unit (ICU) as a result of severe acute respiratory infections (SARIs). METHODS: All patients admitted to one of 206 participating ICUs during two study weeks, one in November 2013 and the other in January 2014, were screened. S...


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