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Peptide-keratin interactions for enhanced hair properties
Carvalho, José; Rodrigues, Ana Rita O.; Ferreira, Tiago; Gomes, Vânia; Pereira, Francisco; Martins, Cátia D. F.; Martins, MadalenaSummary Fusion peptides inspired by natural elastomeric proteins are fused to a keratin peptide (KP) and tested on damaged hair. Here, we report thermal and mechanical tests conducted on treated damaged hair in conjunction with the peptides physicochemical properties, resulting in a statistical multiparametric analysis. Among the parameters, the Youngs modulus and the keratin helix denaturation temperature show...
Cosmetic potential of a structural protein copolymer based on silk, elastin, an...
Mota, Ana Filipa Pereira; Caçador, Marta; Carvalho, José; Tinoco, Ana; Costa, André Dias; Ribeiro, Artur; Gonçalves, Filipa Daniela GomesThe hair cosmetic industry is constantly searching for new ingredients and innovative materials that can help enhance properties, such as softness, shine, shape, and color. However, conventional products contain harmful chemicals. In this study, we developed a biobased alternative using a recombinant protein composed of repetitions of consensus motifs from the structural proteins silk, elastin, and keratin, ter...
Mulheres de Armas: Dados Quantitativos e Perceções das Militares em Regime de V...
Cardoso, António Ideias; Tinoco, Ana; Reis, Cláudio Costa; Vilhena, CristinaNos últimos 20 anos, em certa medida por influência da Resolução do Conselho de Segurança das Nações Unidas n.º 1325, tem-se evidenciado uma crescente consciencialização da importância da integração e participação das mulheres nos diversos domínios da Defesa Nacional, nomeadamente nas Forças Armadas. Radicado na evolução dos efetivos militares, este artigo caracteriza a situação atual da participação das mulher...
Biotechnology of functional proteins and peptides for hair cosmetic formulations
Tinoco, Ana; Martins, Madalena; Cavaco-Paulo, Artur; Ribeiro, ArturCosmetics procedures and products combined with environmental insults and daily routines induce irreversible changes in hair. As result of damage, the hair loses some of its properties like strength, elasticity, and smoothness. Recent studies revealed the positive effects of protein-based cosmetics in providing protection to hair. Additionally, these cosmetic products have also shown a great ability to modify h...
Hair resistance to mechanical wear
Ribeiro, Artur; Martins, Madalena; Tinoco, Ana; Cavaco-Paulo, ArturHair mechanical properties are primary indicators of hair integrity. Here we describe a methodology based on hair's resistance to mechanical wear to evaluate cosmetic treatments. Using a vibrational vortex cycle, we developed a protocol that relies on the plastic deformation and degradation of hair, due to frictional forces between hardened steel balls and hair fragments. We demonstrate that the balls when in c...
Proteins as hair styling agents
Tinoco, Ana; Costa, André; Luís, Salomé; Martins, Madalena; Cavaco-Paulo, Artur; Ribeiro, ArturThe perming of hair is a common styling procedure with negative impact on the overall properties of the hair fibers. Usually, this process uses harsh chemicals to promote the disruption of disulfide bonds and the formation of new bonds to change the shape of hair. Here, we explored bovine serum albumin (BSA), silk fibroin (SF), keratin and two fusion recombinant proteins (KP-UM and KP-Cryst) as new perming agen...
Keratin:Zein particles as vehicles for fragrance release on hair
Tinoco, Ana; Gonçalves, Filipa Daniela Gomes; Costa, André; Freitas, David; Cavaco-Paulo, Artur; Ribeiro, ArturHair perfumes are becoming a trend all over the world and new cosmetic formulations have been developed to address this recent need. In the present study, we developed a system for the controlled delivery of perfumes on hair, based on zein, a protein derived from maize, and on keratin. The Keratin:Zein particles, obtained using different strategies and proportions of zein and keratin, presented a high stability...
Mulheres, paz e segurança
Morais, Diana; Dias, Mónica; Caria, Catarina; Cardoso, António Ideias; Tinoco, Ana; Reis, Cláudio Costa; Vilhena, Cristina; Alves, AndreiaDuas décadas após a adoção da Resolução 1325 do Conselho de Segurança das Nações Unidas, as lacunas no estabelecimento da paz e segurança, relacionadas com as questões de género, são ainda amplas e profundas. Isto levanta questões importantes sobre como a Resolução 1325 e as resoluções subsequentes, sobre a agenda “Mulheres, Paz e Segurança”, impactam as sociedades. Neste artigo, analisamos de que forma os Plan...
Ohmic heating as an innovative approach for the production of keratin films
Tinoco, Ana; Rodrigues, Rui M.; Machado, Raul; Pereira, Ricardo N.; Cavaco-Paulo, Artur; Ribeiro, ArturOhmic heating is a thermal processing method based on the application of electric fields directly into a semi-conductive medium. In this study, we explored for the first time the use of ohmic heating to obtain keratin films. The properties of the films prepared by ohmic heating and conventional heating were evaluated and compared under similar thermal profiles. A lower increase in free thiols' concentration was...
Crystallin fusion proteins improve the thermal properties of hair
Tinoco, Ana; Gonçalves, J. A.; Silva, Carla; Cavaco-Paulo, Artur; Ribeiro, ArturStyling hair with straightening irons is a popular daily hair routine that significantly damage the hair keratin fiber due to the high temperature applied. In this study, we investigate the effect of two fusion proteins based on the human eye D-crystallin conjugated with a keratin-based peptide (KP-Cryst Wt and KP-Cryst Mut) on hair exposed to thermal damage. The mutant form was designed to improve protein stab...