Background: The abuse of synthetic cathinones (SC) is popular among young consumers for recreational purposes and has increased dramatically in the last years. Consequently, SC have been found in the aquatic environment at low concentrations [1]. Since SC are designed to change nervous system function, they may pose unpredictable harmful effects on non-target organisms, such as aquatic invertebrates [2]. Many S...
Pharmaceutical compounds are emerging environmental contaminants that have been detected in various environmental matrices [1]. Their occurrence has been widely reported in domestic and hospital wastewater treatment plants (WWTP) effluents where low removal rates are observed. Even at low levels, they can affect the composition of the microbial communities, and hence disturb the metabolic networks [2]. Aerobic ...
Natural organic compounds such as phytoestrogens and phytosterols found in various plants, as well as mycotoxins produced by fungi, can be found in aquatic environments. The aim of this study was to investigate the occurrence of three different classes of natural estrogenic compounds, i.e., phytoestrogens, phytosterols and mycotoxins, in estuarine water samples from the Ave River estuary. For that, water sample...
Pharmaceuticals often reach wastewater treatment systems where low removal rates are observed. In the present study the potential impact of a mixture of such micro-pollutants on an aerobic granular sludge-sequencing batch reactor (AGS-SBR) was investigated using a lab-scale bioreactor. COD and P- removals were affected due to the load of pharmaceuticals resulting in a decrease of the COD uptake and the P-releas...
In recent decades, the occurrence of pharmaceuticals in the environment has been widely reported due to their high frequency and recalcitrance in many cases. Concerning the chiral pharmaceuticals (CPs) in environmental matrices, the stereochemistry is often neglected and enantiomers are determined together as unique molecules. However, it is well known that CPs might have enantioselective toxicity, rendering im...
Pharmaceutical compounds are emerging environmental contaminants that have received growing attention over the last two decades. Several of these pharmaceuticals currently in use are chiral. Therefore, the evaluation of the enantiomeric fraction (EF) of chiral pharmaceuticals (CPs), during the removal processes occurring in the environment, is crucial for assessing the fate of such micropollutants. Aerobic gran...
Sample extraction is a major step in environmental analyses due both to the high complexity of matrices and to the low concentration of the target analytes. Sample extraction is usually expensive, laborious, time-consuming and requires a high amount of organic solvents. Actually, there is a lack of miniaturized methodologies for sample extraction and chiral analyses. Here, we developed a dispersive liquid-liqui...
Fluoxetine (FLX) is a chiral fluorinated pharmaceutical mainly indicated for treatment of depression and is one of the most distributed drugs. There is a clear evidence of environmental contamination with this drug. Aerobic granular sludge sequencing batch reactors constitute a promising technology for wastewater treatment; however the removal of carbon and nutrients can be affected by micropollutants. In this ...