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Squaramide-based synthetic chloride transporters activate TFEB but block autoph...
Zhang, Shaoyi; Wang, Yan; Xie, Wei; Howe, Ethan N W; Busschaert, Nathalie; Sauvat, Allan; Leduc, Marion; Silva, Lígia C. Gomes da; Chen, GuoCystic fibrosis is a disease caused by defective function of a chloride channel coupled to a blockade of autophagic flux. It has been proposed to use synthetic chloride transporters as pharmacological agents to compensate insufficient chloride fluxes. Here, we report that such chloride anionophores block autophagic flux in spite of the fact that they activate the pro-autophagic transcription factor EB (TFEB) co...
Date: 2019
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Origin: Estudo Geral - Universidade de Coimbra
Author Correction: Squaramide-based synthetic chloride transporters activate TF...
Zhang, Shaoyi; Wang, Yan; Xie, Wei; Howe, Ethan N W; Busschaert, Nathalie; Sauvat, Allan; Leduc, Marion; Silva, Lígia C. Gomes da; Chen, GuoIn the version of this article originally submitted, it was stated that the first three authors (Shaoyi_ Than, Yan Wang, Wei Xie) had contributed equally. However, in the published version this information was missing.
Date: 2019
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Origin: Estudo Geral - Universidade de Coimbra